Study On Epidemiology, Diagnosis And Prevention Of Nosocomial Fungal Infections

Objective To investigate epidemiologic factors, diagnosis and prevention of nosocomial fungal infections. Methods A survey of nosocomial fungal infections was conducted on target patients hospitalized between 2000-2004. The clinical effect of prevention for early fungal infection with fluconazol was retrospectively studied in 41 patients undergoing hematopoietic stem cell transplantation from 2004 to 2005. Results The rate of nosocomial fungal infections increased;Nosocomial fungal infections occurred mainly in respiratory tract and urinary tract;the main pathogens of nosocomial fungal infections were Candida spp..Conclusions The rate of nosocomial infections increased recently. Candida spp are still the main pathogens of nosocomial fungal infections. The fungal infection rate and the mortality in the patients who had been prevented and treated with fluconazol after hematopoietic stem cell transplantation are lower than those who hadn't taken fluconazol.