The Study On Processing Technology And Quality Standard Of Qingre Anchuang Capsule

Qingre Anchuang capsule consists of Flos Lonicerae, Radix Glycyrrhizae, Calculus Bovis, Margarita, Radix et Rhizoma Rhei, Herba Andrographitis, Fructus Gardeniae, Radix Ophorae Tonkinensis and Herba Taraxaci. It has a good effect on treating Acne, Crusted tetter and Epifolliculitis according to clinical experience for more than ten yeas. This TCM formula combines the theory of TCM, the modern research and the clinical experience. It has the function of heat-clearing and detoxicating, cooling blood and eliminating stasis to activate blood circulation, purging pathogenic fire and purgating entrails. It has good effect on preventing and treating the Acne.On the premise of reliable effect in the clinic as well as the properties of the effective component of the medicine, the active position was determined, the preparation process and the optimum extract conditions were screened, then the quality was controlled and the preliminary stability was investigated. Small amount of production of Qingre Anchuang capsule showed that the preparation process was reasonable and practical, the quality was controllable, and the quality of the end product was stable. The best extractive condition was researched by orthogonal design, the effective methods were offered in controlling the capsule's quality by TLC analysis of Calculus Bovis , Radix Ophorae Tonkinensis, Herba Andrographitis and Fructus Gardeniae, The content of Emodin and Chrysophanol was determined by HPLC method. The study afforded a best basis on the quality standardization research of Qingre Anchuang capsule.