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Transarterial Oily Chemoembolization Of Primary Liver Cancer: Analysis Of Therapeutic Effects And Prognosis With Reference To The CT Features Of Arterial Phase

Posted on:2005-02-20Degree:MasterType:Thesis
Country:ChinaCandidate:D W XuFull Text:PDF
GTID:2144360155473299Subject:Medical imaging and nuclear medicine
Abstract/Summary:PDF Full Text Request
Objective To study the correlation between CT features of arterial phase and therapeutic effects and prognosis in patients with primary liver cancer after transarterial oily chemoembolizationMaterials and methods There were 69 patients with primary liver cancer followed up after at least three transarterial oily chemoembolization.Tumors were classified as hypervascular (homogeneous and heterogeneous) or hypovasccular(homogeneous and heterogeneous) based on the degree of lesions enhancement during the hepatic arterial phase before transarterial oily chemoembolization. Patients were classified as responders or non -responders based on follow-up CT evidence of altered tumor size ,lipiodol deposition ,and the appearance of new lesions.Results We classified the 69 patients as 27 responders or 42 non -responders. A statistically significant correlation between the hypervascular pattern and response to transarterial oily chemoembolization was seen; conversely, hypovasccular pattern correlated with non-responders to transarterial oily chemoembolization (X~2=40.481, P<0.001) .Patients were classified as responders livered significantly longer than those classified asnon-responders with 6-, 12-, and 24-month survival rates of 96.30%, 89.89%, and 50.24%, respectively , for responders and 80.95%, 45.28%,and 10.65%, respectively , for non-responders <=Conclusion The vascular pattern of primary liver cancer on the basis of the degree of lesions enhancement during the hepatic arterial phase was relative to the therapeutic effects and prognosis of patients treated by transarterial oily chemoembolization. The vascular pattern of primary liver cancer based on CT arterial-phase scans may be helpful in predicting the therapeutic and evaluating the prognosis.
Keywords/Search Tags:primary liver cancer, TOCE, computed tomography, therapeutic effect, prognosis
PDF Full Text Request
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