Clinical Investigation On Tizanidine Influencing CVA Patients' Upper-limb's Function

Clinical investigation on Tizanidine influencing CVA patients'upper-limb's fumction Objective: CVA patient'hemiplegia caused by upper-moving nervouscenter fault is spastic hemiplegia. We observe that the drug of tizamdine cure different degree spasm and control musde tention to some degree to influence hemiplegic patient's upper-limb, hand, ADL recovery. Material and Methods: Onehudred-twenty hemiplegic patients caused by stroke were recruited and allocated into 2 groups according to muscle tension. A group (muscle tensin is reform Ashworth II lever) there are sixty patients, B group (Muscle tension is reform Ashworth III-IV level) there are sixty patients. A group is divided experimental group and comparable group. A group patients are treated with neuropathic conventional medicine and rehabilitation train. The drug of tizandine lower the muscle tension from reform Ashworth II lever to reform Ashworth I in experimental group. B group is divided experimental group and comparable group. B group patients are treated with neuropathic conventional medicine and recovery train. The drug of tizandine lower the muscle tension from reform Ashworth III IV level to reform Ashworth II level in experimental group. All patients are praded according to Shang tianmin level for upper-limb, hand, and Fim grade for ADL, self-nurse ability before therapy and eight weeks after therapy. Result: Experimental group isn't obvious different in contrast to comparable group after therapy for the upper-limb function in A group (P>0.05). This indicate that there's no influence for the upper-limb fumction when the drug of tizandinine lower the muscle tension from reform Ashworth II level to reform Ashworth I level. Experimental group is obvious difference in contrast to comparable group after, therapy for the upper-limb function in B group (P<0.01). This indicate that there's influence for the upper-limb function when the drug of tizandine lower the muscle tension from reform Ashworth III~IV level to reform Ashworth II level. All patient's upper-limb function is obvionsly improved in contrast to the primary situation (P<0.01). This indicate that rehabilitation therapy and the drug of Tizamdine or the simple rehabilitation therapy can obviously improve the upper-limb function. A group's patient's hand function isn't improved in contrast to primary situation (P>0.05). This indicate that rehabilitation therapy and the drug of Tizandine or the simple rehabilitation therapy can't improve the hand function. Experience group is obviously improved in contrast to primary situation for the hand function in B group (P<0.05). This indicate that the drug of Tizanidine and rehabilitation therapy hand improve the hand function. Comparable group isn't improved in contrast to the primary situation for the hand function in B group (P>0.05). This indicate that simple rehabilitation therapy can't improve hand function. Experimental group isn't difference in contrast to comporable group after therapy for the hand function in all patients (P>0.05). This indicate that the muscle tension improvement can't influence the hand function. All patients'ADL is improved in contrast to primary situation (P<0.01). This indicate that rehabilitationtherapy and the drug of Tizanidine or the simple rehabilitation therapy can obviously improve the ADL ability. Experimental group isn't difference in contrast to comparable group after therapy for the ADL ability in all patients (P>0.05). This indicate that the muscle tension can't influence the patients'ADL ability in all patients. FIM score include six sides contents, Because self-nurse ability is closely associated with the upper-limb and the hand, We list this project score. All patients'self-nurse ability is improved in contrast to primary situstion (P<0.01). This indicate that rehabilitation therapy and the drug of Tizanidine or the simple rehabilitation therapy can obviously improve the self-nurse ability. Experimental group isn't difference in contrast to comparable group after therapy for self-nurse ability in A group (P>0.05). This indicate that there's no influence for the self-nurse ability when the drug of tizanidine lower the muscle tension from reform Ashworth II level to reform Ashworth I level. Experimental group is obvious difference in contrast to comparable group after therapy for self-nurse ability in B group (P<0.05). This indicate the drug of Tizandine can improve self-nurse ability when it lower the muscle tension from reform Ashworth III, IV level to reform Ashworth II level. In reform Ashworth III IV level, the drug of Tizandine can't influce the ADL ability, but can influence a certain subject. Conclusion: 1. The drug of tizandine can't influence the upper-limb function, the hand function and ADL ability during the recovery period when it lower the musde tension from reform Ashworth II level to reform...