The Clinical Study Of Bushentongbi Decoction On Ankylosing Spondylitis

In the study, baseing on the theory of TCM and combination of Traditional Chinese with western medicine, Systematically and intensively explores the etiological factors and therapeutic methods for ankylosing spondylitis(AS) from both theoretical and clinical aspects.The TCM theories of treatmeant according to syndrome differentiation were used clinically to probe into the possible cause, pathogenesis, management method and prescription of ankylosing spondylitis. The research considers the blocking of kidney and Du Mai as the main causes of AS, and accordingly adopts strengthening kidney and Du Mai, eliminating toxin, activating bloodas the main therapeutic method. In the study, Bushentongbi decoction is taken as the test group with Yishenjuanbi pills as control one and with 30 subjects in each group. The results show that the controlled and effective rate in test group is 63.33% with 26.67% in control one(P<0. 01). But the total effective rate shows no difference in two groups. In the aspect of of eliminating symptoms, improving laboratory index and antidestruction of bone, the test group is superior to the control one(P<0. 01 or P<0. 05). The study shows that the curative effect and the relief of the symptoms in the treatment group are better than that in the control group. The mechanism might be relate to anti-inflammation, relieving pain, regulating immunological function, improving hemorheological index and bettering microcirculation, etc. In such view, it treats AS effectively in poly-side.