The Clinical Study On The Effect Of Long Bei Capsule In The Treatment Of Knee Osteoarthritis In Postmenopausal Women

The Osteoarthritis (OA) is a kind of chronic progressive degenerative disease of the bone and joint. With the degree along with the aging in population aggravating, the Osteoarthritis (OA) sufferer's quantity also will increase immediately and obviously.The clinical doctors like to use COX-2 depressants to treat the Osteoarthritis sufferers. Although this kind of medicine's side effects to the stomach and intestines are lower than that of the non-steroid anti-inflammatory drug (NSAIDs) .And these is little harmful effects to the renal function.But still there are much disputes in the reliability problem to the cardiovascular aspect. As early as in 1805, Haygarth have discovered that the Proliferative arthritis is easily happen to the female,and especially easily happen in the femal who is in the age of physiological postmenopause. In 1925, Cecil and Archer firstly put forward that the Osteoarthritis (OA) has something to do with the estrogen.They named this kind of joint disease "postmenopausal Osteoarthritis ". The Epidemiology and the clinical research datas show that there is sexual difference in the Osteoarthritis' (OA) prevalence rate and clinical performances.The incidence is obviously higher in the female who are in the age of after middle than the male in the age of after middle, and the symptom is more serious than the male in the age of after middle/This prompt that the estrogen and its change during menopause maybe act as a medium in the Osteoarthritis' (OA) pathogenesis. Because the oestrogen replacement therapy has been used widery,it provides a new proch to study the relationship between Estrogens and the Osteoarthritis (OA). The recent studies show that the oestrogen replacement therapy not only can treat osteoporosis but also can protect the the Osteoarthritis (OA).For example, spector's[47] and vingar's[48] studys show the oestrogen replacement therapy can protect knee and coxa's osteoporosis. All these facts show ectogenesis estrogens have a indeed protect effect to the Osteoarthritis (OA).The Long Bei capsule has been using to treat the people who suffers from the Osteoarthritis in Guang Dong Hospital of traditional Chinese medicine.The Long Bei capsule is a pure traditional Chinese medicine pharmaceutics.In the aspect of treating the...