| Purpose. To study the value of MR diffusion weighted imaging (MR-DWI) in evaluating the severity of hepatic cirrhosis. Materials and Methods. DWI were employed on 55 persons, including 19 normal people and 36 cirrhotic patients with different severity grouped by Child-Pugh grading system. And then the values of apparent diffusion coefficients (ADC) were calculated and compared. Results. ADC values of normal livers ranged between 1. 60 mm2/sec× 10-3 to 2. 30 mm2/sec × 10-3, with the mean value of 2. 01 + 0. 20 mm-2/sec × 10-3, while the ADC extent of cirrhotic liver was 1. 12-2.05 mmVsecX 103, with the mean value of 1.56 + 0.24 mm2/sec × 10-3. ADC values of the former ones were higher than the latter, and there was significant difference between them (P<0. 01) . With the development of hepatic cirrhosis, ADC values decreased. They were 1.76+0.20 mm2/sec × 10-3, 1.58+0. 13 mm2/sec × 10-3 and 1.33+0.17 mm2/sec × 10-3 for Child A, B, C degree respectively, and significant differences were found among them (P<0. 01).Conclusion. MR diffusion weighted imaging DWI is a useful tool for evaluating the severity of hepatic cirrhosis.
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