Perimenopausal Syndrome (PMS) is a high-morbidity common disease.It is a group of syndrome that is caused by the fluctuative decrease of the woman'estrogen level in her menopausal period. This syndrome'main peculiarity is vegetative nerve functional disturbance and psychonosema or psychologic disturbance is accompanied. This article elaborates systematically the pathogeny and therapy development of this disease from both sides of modern medicine and traditional Chinese medicine.My tutor, professor wang is guided by the theory of Chinese medicine, He thinks deficiency of Kidney-yin is main mechanism of PMS and adopted the method of nourishing Kidney-yin to treat 20 patients (the drug is Zishenangengtang) and selected 20 patients as control group (thedrug is Gengnianan capsule) We observed their clinical symptoms, measured endocrine hormone level before and after treatment.The result proved that Zishenangengtang could obviously relieve their symptoms, increase E2, reduce FSH and its effect was prior to the control group. It could also regulate the immune function of their bodies. According to this, we considered that Zishenangengtang'curative effect was obtained through adjusting HPOA, also through improving bodies immune function probably. |