| Objective: To observate the clinical effects of Youbiqing Granule on preventing relapse from postoperation in patients with condyloma acuminatum and to investigate its effective mechanism based on cellular immunity levels.Methods:136 cases of condyloma cauminatum were divided randomly into the trial group (71cases) and the control group(65cases). In order to investigate effective mechanisms and effects of Youbiqing granule, the former was treated by Youbiqing granule and the later by Poly I:C. The clinical effects of preventing relapse from postoperation, and the levels of T-lymphocyte subsets,IL-2 and sIL-2R in sera, were assayed before and after therapy. As for the normal control group, the above indexes were assayed only one time.Results: The Youbiqing granule markly reduced the postoperative relapse rate in the patients with condyloma acuminatum which was better significantly than that of poly I:C(P<0.01); it has a significant effect which was better significantly than that of poly I:C(P<0.01) to adjust the levels of T-lymphocyte subsets, IL-2 and sIL--2R in sera, but it couldn'd adjust the abnormal IL-2 and sIL-2R to normalization.Conclusions: Youbiqing granule has relatively good effects to prevent relapse from postoperation of condyloma acuminatum and its effective mechanism has correlation with immune adjustion of T-lymphocyte,IL-2 and sIL-2R.
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