The Experimental Study Of Acupunvture On The Influenc Of GSH-PX,NO And Apoptosis Cell To The Rats Of Vascular Dementia

Vascular dementia (VD) is a common kind of Dementia caused by cardiovascular diseases. It is a significant subject in medical science how to prevent or retard the pace of this disease. In recent decades, western medicine and traditional Chinese medicine used in VD continually turned up and relative reports on acupuncture have been increasing. But the experimental studies on acupuncture treatment are not many. So we adopted this method to do the experimental study .Purpose To study the effect of acupuncture on the learning dysmnesia of VD rats activity of GSH-PX and content of NO and to observe injured neuron in hippocampal region. Method To select 36 healthy Wistar rats which were divided into 4 groups. They included negative injury group, model groupx acupuncture group and medicine group. In the experiment, we adopted 2-VO to duplicate model VD and carried on acupuncture treatment on the baihui-dazhui acupuncture point of rat heads. By the end of the study, we examine the memory ability of rats in according to the shuttle test. Finally, the biochemistry changes were studied. Results Modelling led to the reduction of model animal's learning and memory ability and promote the activities of GSH-PX, diminish the content of NO cerebral issues. Conclusions Acupuncture in baihui-dazhui could improve the learning and memory ability of model animal and promote the activities of GSH-PX and decrease the content of NO. And it can promote the restoring function of injured neuron in hippocampal region.