The Clinic Study About Treating Of Pleural Effusion With Pulmonary To Lung Cancer By Guitingbaihe Decoction Combined With Chemotherapy Through Pleural Perfusion

Objective: To investigate the curative effects of Guitingbaihe decoction combined with the chemotherapy through pleural perfusion on the pleural effusion with Pulmonary QiXu and QiYinLiangXu syndromes subsequent to the lung cancer.Methods: 50 inpatients of pleural effusion subsequent to the lung cancer were selected, and divided randomly into treatment group (treated with the Guitingbaihe decoction combined with chemotherapy through the pleural perfusion) and control group (treated with only chemotherapy through the pleural perfusion) after stratification. The clinic curative effect was observed and compared.Results:The treatment group had a better curative effect than the control group, and there was a significant difference between these two groups(p<0.05). There was no difference between the treatment group and the control group on the effective rate of curing the primary focus of pleural effusion subsequentto lung cancer (p>0.05). (3)As to the effect of ameliorating the main symptoms, the scoring method of Karnofsky was used to evaluate the quality of life. The results showed that there was a remarkable difference between the treatment group and the control group, and the former was better. (4)On alleviating the toxicity and side-effect of chemotherapy, the therapy of Chinese traditional medicine Guitingbaihe decoction combined with chemotherapy had a slighter side effect of alimentary canal(p<0.05).But there was no obviously difference between both groups on the effect of bone marrow depression and impairment of liver and kidney's function. In both groups, there was no significant difference between Pulmonary QiXu syndromes and QiYinLiangXu syndromes on syndromatic curative effect (p>0.05 ) .Conclusion: Therapy of the combination of Guitingbaihe decoction and chemotherapy through the pleural perfusion has a satisfactory curative effect on the pleural effusion with Pulmonary QiXu and QiYinLiangXu syndromes subsequent to lung cancer. Its mechanism is that both therapies have a cooperative effect and the synthesis effect is better than the effect of chemotherapy only. In both groups, there was no significant difference between these two syndromes on syndromatic curative effect.