Research On The Relationship Between The Essential Hypotension Patients'Ambulatory Blood Pressure Cardiac Function And Their TCM-Syndrome

Research on the Relationship between the EssentialHypotension Patients' Ambulatory Blood PressureCardiac Function and Their TCM-SyndromeMajor: Clinic of the Traditional Chinese Medicine Postgraduate: Li Cuiyun Tutor: Prof. Lin SongboVice Prof. Zhou GuoyingABSTRACTObjectives: To observe the essential hypotension patients' average blood pressure and their regulation by the technology of Ambulatory Blood Pressure Monitoring(ABPM), To research the pathogenesis of essential hypotension , especially the cardiac function by the echocardiograra, To research the difference between Qi-deficiency TCM-syndrome and Yin-deficiency TCM-syndrome in cardiac function.Results:1. 50 patients were observed, 39 female cases > 11 male cases, 8 patients have family history of Essential Hypotension, 48 percent patients' body weight 10 percent lower than the standard weight. 67 percent have emotional stress in work. There is no obviously habit in diet. 60 percent have introversion temperament. In complaint: 48 cases dizzy , 13 cases headache , 48 cases fatigued and weak , 41 cases forgetful , 21 cases palpitation -. 6 cases have oppressive sensation in the chest , 5 cases have poor appetite. The average blood pressure were 88. 5?. 5/56. 4?. 7mmHg.2. The ABPM indicated that: the average blood pressure in 24 hours x daytime and night were 100.9 /62. 1 mmHg > 102.8 /63.7mmHg and 95 756.9 mmHg. Most" oT TTIe blood pressure decreased during early dawn or at 3 O'clock in the afternoon. The diastolic pressure decreased more obviously than the systolic blood pressure.3. The result of cardiac function by echocardiogram showed that: ㏕he patients' Interventricular Septal Thickness(IVST) , Left Ventricular Mass (LVM) , Left Ventricular Mass Index (LVMI) and Mean Wall Thickness at Diastole(MWTD) decreased significantly, while the left ventricular internal diameter at end-systole(LVDs) and the left ventricular internal diameter at end-diastole (LVDd) decreased, p<0. 01. (2) The patients' left ventricular ejection fraction(EF) , FS, end-systolic stress on the left ventricular wall (ESS) and the cardiac contractility descended obviously, but the EF was still in the normal field. (3) The patients' early-diastolic deceleration(DC) descended significantly, p<0.01. There was no difference in statistics of the cardiac diastolic function.4. The indexes of the cardiac function of Qi-deficiency TCM-syndrome and Yin-deficiency TCM-syndrome in Essential Hypotension showed that: The indexes of IVST , left ventricular posterior wall thickness(PWT) , LVM and MWTD in the Qi-deficiency TCM-syndrome decreased more significantly than that in the Yin-deficiency TCM-syndrome, so did the FS, ESS and E/A.Conclusion: The Essential Hypotension is commonest in the young female. The disease is associated with constitution and genetic factor, as well as emotional stress in work. The blood pressure of Essential Hypotension always below normal level in some period of one day, especially the diastolic blood pressure. The patients' cardiac function descended relatively, especially the systolic cardiac function of Qi-deficiency TCM-syndrome changed more significantly than that of Yin-deficiency TCM-syndrome. So if take medicine increasing the cardiac contractility .meanwhile with the Chinese herbal invigorating Qi, strengthening the spleen and reinforcing the heart, will get good curative effect.