The Studies Of Toxicity Of Lentinus Ramasii Lloyd And Pluteus Phlebophorus

The Lentinus ramasii lloyd and Pluteus phlebophorus, which grow up after raining, distrubute in the Xinglongshan nature protected area in Gansu Province. The toxicity of the Lentinus ramasii lloyd and Pluteus phlebophorus were studied with the indicators including the fatal dose of the Black worms and Cyprinus flammans, the weight gain and the pathological changes in livers, kidneys and spleens of the Kunming Mice. These tentative studies about their toxic effects provided a scientific basis for the toxicological effects of the Lentinus ramasii Lloyd and Pluteus Phlebophorus to the mammals. The results are as following:1. After feeding with the juice of the Lentinus ramasii lloyd, the Black worms, Cyprinus flammans were dead in 48 hours. However, the mice' s observation is not the same as the formers. These mice still survived with feeding with the juice, but appetite dropping, low-spirited, slow-acting. These means that in the initial exposured time, the digestive system of the animals had injuried seriously. According to the pathological changes in livers, kidneys and spleens of the mice who were feeding with the juice of the Lentinus ramasii lloyd, the conclusions can be confirmed that livers, kidneys and spleens were damage seriously with gross anatomy and the histology inspecting, and as the dose increasing, the degree of damaging of three organs in mice also increased. According to the "standards of compounds' acute oral toxicity" , the biological toxicity of the Lentinus ramasii lloyd is low-toxicity.2. After feeding with the juice of the Pluteus phlebophorus, the Black worm, Cyprinus flammans were dead in 48 hours. However, the mice' s observation is not the same as the formers. These mice still survived with feeding with the juice, but appetite dropping, low-spirited, slow-acting. These means that in the initial exposured time, the digestive system of the animals had injuried seriously, but the extent of damage is inferior to the Lentinus ramasii lloyd' s. According to the pathological changes in liver, kidneys and spleen of the mice who were feeding with the juice of the Pluteus Phlebophorus, these conclusions can be confirmed that with gross anatomy and the histology inspecting, livers and kidneys were damage seriously, but the spleens were normal, and as the dose increasing, the degree of damaging of livers and kidneys in mice also increased. According to the "standards of compounds' acute oral toxicity" , the biological toxicity of the Pluteus Phlebophorus is low-toxicity.