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The Research Of Flavonoid From Phellinus Igniarius

Posted on:2012-07-26Degree:MasterType:Thesis
Country:ChinaCandidate:C LiuFull Text:PDF
GTID:2143330332499249Subject:Bio-engineering
Abstract/Summary:PDF Full Text Request
Phellinus igniarius has been used as traditional medicine in the world. Until now, there are many chemical components have been extracted from the fruit bodies of Phellinus igniarius such as polysaccharrides, flavonoids, which are the main active composition and terpenoid. Many studies found that Phellinus igniarius has anti-tumor, anti-oxidation, anti-mutation, improving inflammatory, antibacterial, antiviral, and so on. Flavonoid is a group of polyphenolic compounds which can be found in seeds, fruits, tea, vegetables, and green leaves. They execute a wide range of biological effects, such as antibacterial, antiviral, anti-inflammatory, antiallergenic, and vasodilatory actions. Based on the predicted physicochemical properties,some theoretical studies on the activities of flavonoids were done. Many studies about Phellinus igniarius mainly focused on the optimization of submerged fermentation parameters for high-yield flavone-producing strain, the structures and activities of polysaccharides. The studies about flavonoids were poor. This paper studied the extraction and isolation, the molecular structures and the activities of anti-Xanthine oxidase.Firstly, we obtained the intact flavonoid from Phellinus igniarius after extraction with 90 % enthanol and . The total flavonoids were detected through and quantitated with . Then we purified the main components with HPLC and got two component parts, which had the similar molecular weight. The activity experiment shown that the flavonoids from had anti-Xanthine oxidase activity and revealed dependence on dose.These data in this paper was important for the studies on the isolation and purification and molecular structures and activities of lavonoid of Phellinus igniarius, in addition which was helpful for the developing of Phellinus igniarius.
Keywords/Search Tags:Flavonoid
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