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Effect Of Yiqi Buxue Traditional Chinese Medicine Combined With Low Molecular Weight Heparin On Coagulation Index In Artificial Hip And Knee Replacement Patients

Posted on:2015-06-04Degree:MasterType:Thesis
Country:ChinaCandidate:W Z FanFull Text:PDF
GTID:2134330467453166Subject:Orthopedics scientific
Abstract/Summary:PDF Full Text Request
Aim:To study the yiqi broken blood traditional Chinese medicine combined low molecular heparin coagulation indexes in patients with artificial hip and knee arthroplasties.Method:The Subject acquisition in February2010-February2014in wangjing hospital of China academy of traditional Chinese medicine joint second treatment, and included in the standard data of120cases of patients. Of the120cases of knee, hip arthroplasty patients were randomly divided into four groups, each group30cases, traditional Chinese medicine, western medicine group respectively, the joint group, blank control group. Patients after joint replacement, four groups all use physical therapy machinery to prevent blood clots. Among them, the Chinese medicine group with yiqi broken blood medicine (postoperative day one, to the patients with yiqi broken blood herbal medicinal broth water,1/day,2times/day, sooner or later served treatment for14days). Joint group using yiqi broken blood medicine (after the first day, give yiqi broken blood in patients with Chinese medicine medicinal broth water,1/day,2times/day, sooner or later served treatment for14days)+low molecular heparin calcium (postoperative day one, abdominal subcutaneous injection of4100IU/time,1time/day, with14days) to prevent blood clots; Western medicine group began using low molecular heparin calcium () before usage with anticoagulation; Blank control group no anticoagulant drugs and traditional Chinese medicine intervention. USES the function of blood coagulation analyzer and gbACT reagent to detect the activation of four groups of patients before and after drug intervention whole blood coagulation time (activated coagulation time, ACT), fibrous protein aggregation rate (clotrate, CR) and the incidence of lower limb venous thrombosis, with preoperative night,2h,24h after surgery, postoperative with2weeks after coagulation indexes as well as the patients had the flow and the result of lower limb venous colour to exceed as a parameter, matching t test.Results:1. Blood coagulation indexes:①The selected group of120patients with ACT, CR value indicates that, on the eve of the4groups were comparable with baseline.②Postoperative2H patients in the four groups were compared with the eve ACT value decreased, CR increased. ACT, CR values varied between the four groups were no statistical significance.③Postoperative24h traditional Chinese medicine group, western medicine group, combined group patients after ACT values were compared with postoperative2H increased (P<0.05), blank control group without intervention by the change of ACT value has no obvious statistical difference. The changes of ACT value, the combined group than the other two groups significantly (P<0.05), western medicine group ACT value than traditional Chinese medicine group (P<0.05). Postoperative24h combined group and Western medicine group CR value compared with postoperative2H decreased (P<0.05), Chinese medicine group and blank control group, changes of CR value of no statistical significance (P>0.05).④Two weeks after operation, four groups of patients with ACT were compared with postoperative24h increased (P<0.05), and the western medicine group ACT value increased more obvious changes. Joint group and Western medicine group and CR value is on the first postoperative day (P<0.05), Chinese medicine group decreased compared with those before treatment CR value changes of no statistical significance (P>0.05).⑤After two weeks, the United Group, western medicine group after administration of ACT values were compared with the eve rise (P<0.05), and the western medicine group increases more significantly (P<0.05or P<0.01). Two weeks after surgery of traditional Chinese medicine group was no significant difference in ACT value and ACT value on the eve of operation group (P>0.05). The two week group, western medicine group were lower than that of CR on the eve of decrease postoperative (P<0.05), while the traditional Chinese medicine group compared with the change of CR value on the eve of no statistical significance (P>0.05).2. The incidence of venous thrombosis of the lower limbs:120patients there were18cases with venous thrombosis of the calf muscle, the total incidence rate of15%, the group of30patients, the formation of calf muscular venous thrombosis in2cases, the incidence rate was6.66%,30cases of Western medicine group, the formation of the calf muscle venous thrombosis in3cases, students rate was10%,30cases of Chinese medicine group, the formation of the calf muscle venous thrombosis in5cases, ratio of16.67%;30cases of patients control blank, formed in8patients with venous thrombosis of calf muscle, ratio of26.67%.3. Postoperative drainage volume:four groups of patients after joint replacement drainage had no significant difference.Conclusion:The methods of Replenshing-Qi and Removing-blood stasis on patients (ACT, CR) has the effect of regulating, prevent venous thrombosis of the lower limbs of the synergistic effect of low molecular weight heparin at.
Keywords/Search Tags:Coagulation Parameters, Deep vein thrombosis, the methods ofReplenshing-Qi and Removing-blood stasis
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