Optimization Research On Air Environment System Of Laboratory Animal Room Based On CFD

The 21st century is time of life sciences. Every country is being involved in dramatic competition in the fields of life science's high technology. The laboratory animals has already become the basis and crucial supporting factor for the development of life science, such as biology, medical science, pharmacy, chemical industry, agriculture, environmental protection, spaceflight, commodity inspection , war industry, medicines safety evaluation, and experiment result. In scientific research, the laboratory animal is called "alive precise instrument". Product quality assessment, accomplishment appraisement and the academic exchange between world are asked to uses identical standard laboratory animals, laboratory animal room where is the environment for laboratory animal growth and life gets more and more attention of scientists, laboratory animal room environmental quality is the most basic guarantee for laboratory animal quality, Along with GMP(Good Manufacturing Practices) was implemented further and life science was develop further, the important role of laboratory animal room environment control will be also incarnate step by step, scientific research about laboratory will be further strengthened.Compared with normal air conditioning, a lot of problems about clean air conditioning system in laboratory animal room have not got appropriate treatment and caused enough attention because of its short developing history, the ubiquitous problem is that we have not considered energy-conservation in purpose of reaching the clean standard in the systematic design, which caused a large energy wasting, in addition some problem still exist, such as the poor effect of controlling, the vague check-and-accept standard. All these problem all involve the control of the cleanliness within the laboratory animal room, and influence the quality of the laboratory animal directly, which will surely influence the accuracy of the animal experiment.The research paper aims at optimizing the indoor air distribution environment, improve the quality of laboratory animal on the basis of conserve energy, after summarizing and explaining the history, current situation and development trend oflaboratory animal room and its environment control in an all-round way, This subject combine a certain actual project, study the problem of the laboratory animal room environment control in detail through CFD for the first time, study the relationship among the cleanliness, air distribution and by field survey and simulation analysis. And has followed testing to this operation and management of the laboratory animal room, then the suitable air distribution and air change rate were found, Form a practicability air distribution and pressure differential control, at the same time, adopt the optimized systematic design scheme, achieve the clean and energy-conserving goal, offer reference for standard formulation, project design and construction, operation management of the environmental control system, etc..This paper discussed mainly following several questions:1 , With the regarding as the breakthrough point of a project, the current indoor air distribution in typical laboratory animal room have been introduced, thought CFD simulation, Analyzed and compared several purification result in different air distribution, and analyzed the influence of cages and its way to put in detail. Indicated by technological economic analysis, ceiling diffuser and linear grille supply air and exhausting air in underside is the acceptable air distribution, and different air distribution have correspondingly suitable cages way to put.2, The upper limit of air change rate has been put forward. Regard current typical air distribution of ceiling diffuser supply, return in the corner as research object, we can find its upper limit of air change rate is 24 changes pre hour, if the air change rate reach 24 changes pre hour, it is no use for raising the cleanness in laboratory animal room by raising the air change rate.3, Simulated and analyzed the indoor contamination distributing in different air change rates, under the guidance of the indoor cleanliness, 12 changes pre hour air change rates have been drawn as best one, carried on energy-conservation analysis with current air change rates. Results indicate, if the air change rates have been adopted which recommend by this paper, 33.3% energy can be saving in the whole system.4, The pressure differential of laboratory animal room has been simulated and analyzed in detail. Through the CFD simulation, the indoor and outdoor pressuredifferential of have been analyzed and calculated, the high direction of the windward side change function has been drawn and the place of the biggest pressure has been found, the rationality of pressure differential that the standard stipulates have been verified.5, The experience that the author participates in the design and construction of the laboratory animal room have summarized, the environmental control system of the Nanhua university SPF laboratory animal room have been introduced. According to the national regulation standard method, have followed testing to this air environment in the laboratory animal room, the result of measuring have been analyzed, and contrast the test result and simulation result, the appearing question while designing and operating have been analyzed.