Quantitative Determination Of Oxymatrine And Matrine In Rat Plasma By Capillary Electrophoresis With Stacking Induced By Moving Reaction Boundary

Capillary Electrophoresis (CE) is one of the most powerful analytical separation techniques. Compared to TLC and HPLC, HPCE is superior in terms of the speed, high resolving power and small amounts of samples and reagents required. Now it is widely used for the analysis of drugs and metabolites and become a powerful technique for the analysis of physiological samples gradually. But the limits of detection (LOD) for capillary electrophoresis (CE) are constrained by the dimensions of the capillary. For example, the small volume of the capillary limits the total volume of the sample that can be injected into the capillary. In addition, the reduced path length hinders common optical detection methods such as UV detection.Many different techniques have been developed to improve the LOD for...