Study On Mechanism And Process Of Semicontinuous Extraction And Separation On Effectual Components From Plants By Inner Ebullition

Extracting effectual components from plants is basic of production of natural medicament. The traditional extracting methods always have disadvantages such as long extracting time, high solvent consumption, and low extracting ratio. However, modern extracting methods such as ultrasonic extraction and microwave extraction, need large investiment of equipments, and the operations are complex; thus they are difficult to be applied in industrial scale. Therefore, thorough studying on extraction process, improving traditional technics using new techniques and solving existent problems, become important tasks of natural medicament's production.Semicontinuous extraction by inner ebullition was put forward in this paper. Inner ebullition was presented to enhance the mass transfer inside porous media on general condition. The method of inner ebullition included two steps: firstly, a small quantity of a low boiling point release-solvent was used to saturate the plant from which the effectual components were to be extracted; then a hot solvent with a boiling point higher than that of the release-solvent was added, so the release-solvent inside the plant is heated to boil by hot solvent, and the mass transfer inside was turned to convectional transport, thus the process was enhanced. Experiment on static purification of chlorogenic acid using the D101 macroporous resin was taken to simulate the process of extracting effectual components from plants. The results indicated that mass transfer reached the highest level when inner ebullition was happened.