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Oscillating Chemical Reactions And Their Applications In Pharmaceutical Analysis

Posted on:2006-05-14Degree:MasterType:Thesis
Country:ChinaCandidate:Z X ZhangFull Text:PDF
GTID:2121360182955683Subject:Analytical Chemistry
Abstract/Summary:PDF Full Text Request
Part Ⅰ Oscillating chemical reactions and their applications inpharmaceutical analysisIn recent years, more and more self-organized phenomenon have become of great interest across of wide range of scientific research. In this section, we described the theoretical and experimental development of oscillating chemical reactions, conditions of chemical oscillating reactions; The mechanisms of chemical oscillating reactions and their applications in analytical determination were also discussed in brief. Finally, we mentioned the importance of these reactions in the field of chemistry, biochemistry and engineering.Part Ⅱ Perturbation of cocaine hydrochloride for the B-Z oscillating chemical system and its determination of the concentrationAn analytical method for the determination of the cocaine hydrochloride is established by studying its perturbation on the B-Z oscillating chemical system. The best reaction condition are reported.The results show that the adding of cocaine hydrochloride can change the oscillating amplitude and the change of the oscillating amplitude is linearly proportional to the concentration of cocaine hydrochloride, which is over the range of 4.98×104 mol·L-1 -2.44×10-6 mol·L-1, with the regression coefficient of 0.9987. The method is used to determine sample,a satisfactory result is obtained.Part Ⅲ Perturbation of dicaine hydrochloride for the B-Z oscillating chemical system and its determination of the concentrationA novel method was developed for the determination of the dicaine hydrochloride by the perturbation caused by different amounts of dicaine hydrochloride on the B-Z oscillating chemical system. Ranging from 3.85 × 10-4 mol·L-1 - 4.98×10-7 mol·L-1 the change of oscillating amplitude is second-order polynomial to the concentration of dicaine hydrochloride, with a good correlation coefficient of 0.9979. The method is used to determine sample,a satisfactory result is obtained.Part IV Perturbation of dopamine for the B-Z oscillating chemical system and its determination of the concentrationA new method has been established for the determination of the dopamine by the perturbation caused by different amounts of dopamine on the B-Z oscillating chemical system. The results show that the adding of dopamine can change the oscillating amplitude and the change of the oscUlating ajnpjj&dg j§ linearly proportional to the concentration of dopamine, which is over the range of 1.45X lO^mol-L"1 — 9.70 X 10'7 mol-L"1, with a good regression coefficient of 0.9978 and a standard deviation of 0.17%. Detection limite is 1.2 X10"7 mol.L"1. The interference was also studied.
Keywords/Search Tags:Pharmaceutical
PDF Full Text Request
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