Numerical Analysis Of Microfluid State In Bone Tissue Engineering Scaffolds

In recent years tissue engineering developed a new subject, as tissue engineering and rapid prototyping technology continues to develop, based on rapid prototyping technology, tissue engineering design, manufacturing and its internal porous network of micro-fluid state research is also ongoing in-depth.In this paper, research ideas are firstly designing the internal structure of artificial bone, followed by analyzing the micro-fluid phenomenon, and finally when scaffold and cells are cultivated in the bioreactor, studying pressure on the impact of mass transfer in theory. Around these ideas, carried out the following research work:Firstly, this paper analyzed the internal structure of bone, and explored artificial design, modeling methods, both at home and abroad, and on this basis analyzed of simplified model of the internal structure of artificial bone.Secondly, the use of FLUENT analyzed the impact on velocity of liquid at different angles between microtubule and main pipe, calculated the two-phase flow of cells and nutrient in the scaffold when perfusing, and analyzed and compared the flow field of two different structure in the cell density distribution, two-phase velocity distribution and pressure distribution. So as to lay a foundation in designing the internal structure of artificial bone.Then it studied the flow characteristics of gas and liquid in micro-tubes. By changing the gas flow and liquid flow and using simulation methods, it studied their own situation and the impact on flow pattern, and compared with the predecessors'observed flow patterns. Using of FLUENT for many parameter simulation, it protracted the flow pattern map, and compared with Triplett chart.Finally it analyzed mass transfer process in internal bone and pulse pressure on the impact of mass transfer in theory.