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The Effect Of Magnesium On The Rat Body's Antioxidant System

Posted on:2007-04-18Degree:MasterType:Thesis
Country:ChinaCandidate:A P SunFull Text:PDF
GTID:2120360185979450Subject:Prevention of Veterinary Medicine
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Magnesium is involved in antioxidant defense mechanisms. Magnesium-dificient animals are more susceptible to free radical injury , supporting the hypothesis that magnesium deficiency reduces the threshold antioxidant capacity. Inadequate intake of these nutrients has been associated with some disease, where pathogenic role of free radicals issuggested. This article is related to magnesium influences the body antioxidantsystem.The objective of the first experiment was to dectet the effect of magnesium on the Body's antioxidant system. The feeding periods were divided into 2 growing period of 0 to 3 week and 4 to 6 week. During the first period , the three groups all fed the basal meal diet which contained 0. 07% Magnesium . During the second period, one group still continue to fed the basal meal diet, the other were given 0.27%(supplemented by MgSO4) meal diet, the third group were given 0.27%(supplemented by Proteinate Magnesium) meal diet. The magnesium serum level ;malondialdehyde level and biochemical function analysis were tested at the end of the experiment . During the first period , the level of magnesium in plasma significantly decreased(p<0.05), addtion of 0.2% Mg in diet significantly enhanced the activities of antioxidase (p<0.05), and MDA level significantly decreased (p<0. 05). Here was a significantly difference between organ-magnesium and inorganic-magnesium effect on the activities of antioxidase(p<0.05). Magnesium-defficient animals show an increased susceptibility to an in vivo oxidative stress. Magnesium-replenishment can improve Magnesium-defficient rat's antioxidant capability . The objective of the second experiment was to dectet the effect of magnesium on the body's antioxidant system under the thermal stress condition.The basal meal diet was...
Keywords/Search Tags:Magnesium, Malondialdehyde, Catalase, Glutathioneperoxidase, Superoxidedismutase
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