| Purpose: To evaluate the clinical efficacy of Wenshen Huoxue Jieyu method in the treatment of osteoporosis-type low back pain,and its impact on patients' depression status and quality of life.It is proposed to treat osteoporosis with Wenshen Huoxue Jieyu method,and provide new ideas for the treatment of osteoporosis-type low back pain and depression comorbidity.Material and method: Eighty patients with osteoporosis-type low back pain who were admitted between December 2016 and June 2018 were randomly divided into treatment group and control group according to the method of randomized parallel control.Both groups received routine basic treatment including supplementation.Calcium 1000 mg / d and vitamin D3 800 IU / d.The treatment group was treated with Wenshen Huoxue Jieyu Decoction,and the control group was treated with Zuogui Pill.The two groups were treated for 90 days.The pain visual analogue scale(VAS)was used to compare the values of 5 time nodes before treatment,15 days of treatment,30 days of treatment,60 days of treatment,and 90 days of treatment;according to the chief complaint,the classification method was used for the degree of pain(VRS).The method was performed;and the clinical efficacy of low back pain in osteoporosis was assessed.The quality of life assessment was assessed using the World Health Organization Quality of Life Profile(SF-36).The questionnaires were re-score,the initial scores for the 8 dimensions were calculated,and converted to the final score;The final scores were compared and the data were statistically processed to determine whether the patient's quality of life improved after treatment intervention.The observation of depression status was observed according to the 17-month version of the Hamilton(HAMD)Depression Scale,and the efficacy was evaluated according to the HAMD score reduction rate.Results: 1.Comparison of clinical effects of main low back pain The scores of pain in the lower back pain of the main symptoms in the two groups before and after treatment: There was no significant difference in pain scores between the two groups before and after treatment(P>0.05).The two groups were observed before and after treatment(15 days,30 days,The results of t test showed that the treatment group had analgesic effect after the 15 th day of treatment,and the pain score decreased significantly(t=2.070,P<0.05).The pain score after the 30 th day of treatment was better than that before treatment.There was a significant difference in the decrease(t=3.647,P<0.01).The pain score was significantly different from the pre-treatment decrease after the 60 th day of treatment(t=14.020,P<0.01).The pain score after the 90 th day of treatment was better than that before treatment.There was a very significant difference in reduction(t=21.370,P<0.01).The results of t test showed that the analgesic effect did not work after the 15 th and 30 th day of the treatment,and the pain score was not significantly different from that before treatment(t=1.270,P>0.05/t=1.747,P>0.01).After the analgesic effect,there was a significant difference in pain score reduction(t=2.320,P<0.05).The analgesic effect was more obvious after the 90 th day of treatment.The pain score was significantly different from the pre-treatment decrease(t=7.473,P< 0.01).The two groups were compared between groups.The results of t test showed that the analgesic treatment results of the treatment group were better than the control group on the 15 th,30th,60 th and 90 th day.The treatment group was compared 90 days after treatment.Significantly better than the control group,with a very significant difference(t = 7.258,P <0.01).The treatment group started from the 15 th day of analgesia,and the analgesic effect was fast.After 30 days,the effect lasted for 90 days,and the effect was sustained,which could improve the osteoporosis type of low back pain at an early stage.The control group took effect after 60 days,and the analgesic effect of the treatment group was better than that of the control group.Comparison of the degree of low back pain in different time groups before and after treatment: Compared with before treatment,the Ridit analysis showed that the degree of low back pain was reduced after treatment on the 15 th day,there was a significant difference(U=2.2076,P<0.05);After the 30 th day of treatment,the degree of low back pain was significantly reduced,and there was a significant difference(U=4.4829,P<0.01).After 60 days of treatment,the degree of low back pain was more significant.Very significant difference(U=6.3032,P<0.01);after the 90 th day of treatment,the low back pain was basically relieved,and there was a very significant difference(U=7.0294,P<0.01).Compared with the pre-treatment group,the Ridit analysis showed that there was no significant reduction in the degree of low back pain after the 15 th day of treatment(U=0.1888,P>0.05).After the 30 th day of treatment,there was no degree of low back pain.Significantly reduced,no significant difference(U=0.37762,P>0.05);after 60 days of treatment,the degree of low back pain was significantly reduced,there was a significant difference(U=3.1661,P<0.01);after treatment 90 days later The degree of low back pain was more pronounced and there was a significant difference(U=4.4636,P<0.01).It indicated that the treatment group improved the degree of osteoporosis low back pain better than the control group.Comparison of the effects of low back pain at different time points after treatment in the two groups: Ridit analysis showed that there was a significant difference between the two groups after the 15 th day(U=2.178,P<0.05).After the 30 th day,the two groups were more effective.The difference was(U=2.120,P<0.05).There was a significant difference between the two groups after the 60 th day(U=2.672,P<0.01).After the 90 th day,there was a significant difference between the two groups(U=2.730,P < 0.01).The results showed that the treatment of low back pain in the treatment group was better than the control group in different time periods.2 Quality of life index evaluation Comparison of general health status: According to Ridit analysis,there was no significant difference in the overall conscious health status between the two groups before treatment(U= 1.467,P>0.05),indicating that there was comparability;after treatment,the overall conscious health status of the treatment group was significantly improved.Very significant difference(U=4.624,P<0.01);the overall conscious health status of the control group also improved significantly,there was a significant difference(U=4.101,P<0.01);Significant difference(U = 1.169,P > 0.05).It indicated that the treatment group and the control group had the same effect on the overall self-conscious health status.Health and daily activities: assess the limits of daily activities and health,physical activity,moderate activities,and up and down the building.According to Ridit analysis,there was no significant difference in the health and daily activities between the two groups before treatment(U=0.775,P>0.05),indicating that there was comparability;after treatment,the health and daily activities of the treatment group were significantly improved,which was very significant.Differences(U=4.284,P<0.01);no improvement in health and daily activities of the control group,no significant difference(U=1.786,p>0.05);improvement of health and daily activities of the treatment group after treatment Significantly better than the control group,there was a significant difference(U = 2.274,p <0.05).The treatment group was better than the control group in the treatment group.Analysis of social function status: To assess the daily mental state and health status of the work,and to what extent it affects the normal social interaction between the patient and family,friends,neighbors or the collective.According to Ridit analysis,there was no significant difference in social function status between the two groups before treatment(U=0.204,P>0.05),indicating that there was comparability.After treatment,the social function status of the treatment group was significantly improved,and there was a significant difference(U= 4.182,P<0.01);the social function status of the control group also improved significantly,there was a significant difference(U=3.200,P<0.05);but there was no significant difference between the two groups after treatment(U= 1.147,P >0.05).The therapeutic effect of the treatment group and the control group was similar.3 Depression status evaluation The overall evaluation of depression status before and after treatment in the two groups: After Ridit analysis,the results showed that there was no significant difference in the overall evaluation of depression between the two groups before treatment(P>0.05).After treatment,the overall evaluation of the HAMD scale in the treatment group improved,and the difference was statistically significant.The significance of the study(P<0.05),the overall evaluation of the HAMD scale of the control group did not improve,the difference was not statistically significant(P>0.05),there was no significant difference between the two groups after treatment(P>0.05),indicating Wenshen Huoxue Jieyu Recipe Can significantly improve the state of osteoporosis depression.Depressive mood evaluation before and after treatment in the two groups: After Ridit analysis,the results showed that there was no significant difference in depression between the two groups before treatment(P>0.05).After treatment,the depression in the treatment group improved significantly,and the difference was statistically significant(P<0.01).The control group improved,the difference was statistically significant(P<0.05),but there was no difference between the two groups after treatment(P>0.05),indicating that after treatment,the depression treatment group was equivalent to the control group.The evaluation of sleep factors before and after treatment in the two groups: After Ridit analysis,the results showed that there was no significant difference in sleep status between the two groups before treatment(P>0.05).After treatment,the sleep status of both groups improved,the difference was statistically significant(P <0.05),and the degree of improvement in sleep status of the treatment group was significantly better than that of the control group,the difference was statistically significant(P<0.05),indicating that Wenshen Huoxue Jieyu Recipe can significantly improve the sleep state of osteoporosis.The evaluation of mental anxiety before and after treatment in the two groups: Ridit analysis showed that there was no significant difference in mental anxiety between the two groups before treatment(P>0.05).After treatment,both groups of patients had improved mental anxiety.The difference was statistically significant.The significance(P<0.05),and the improvement of sleep state in the treatment group was significantly better than that of the control group,the difference was statistically significant(P<0.05),indicating that Wenshen Huoxue Jieyu Recipe can significantly improve the osteoporosis mental anxiety state.Conclusion: 1 Wenshen Huoxue Jieyu Recipe has significant analgesic effect on osteoporosis-type low back pain,with quick onset and sustained action.Provide new ideas and treatment options for clinical treatment of osteoporosis.2 Osteoporosis due to low back pain caused by depression,low back pain and depression comorbidity and quality of life decline,Wenshen Huoxue Jieyu method can early pain relief,thereby controlling and reducing the patient's depression and improve the quality of life. |
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