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Clinical Observasion Of Fengtanraodong In Tourette Syndrome Treated With Xifengditantang

Posted on:2019-02-17Degree:DoctorType:Dissertation
Country:ChinaCandidate:Full Text:PDF
GTID:1364330575985065Subject:Pediatrics of traditional Chinese medicine
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Objective:To observe the clinical efficacy of Xifengditantang in treating Fengtanraodong in children with Tourette Syndrome and further markedly desmontrate its scientificity,practicability and clinical applicability.Methods:In terms of dialectics in Chinese medicine,a trial were implemented on 102 subjects of TD children with Fengtanraodong syndrome.In detail,these 102 cases were randomly divided into Xifengditantang group of 50 cases and Changmaxifengpian group enrolling 52 cases.Xifengditantang group was taken well-adjusted Xifengditantang medication while Changmaxifengpian group followed Changmaxifengpian one within a 8-week constant course of treatment.After this first course,good turn-out cases would be treated with same regimen in 4more weeks.Other inefficient cases would be provided new treatments.Results:A significant difference was regconized at(P<0.01)in the YGTSS comparision of the before&after treamentgroups,in which the post-treatment YGTSS reduced than pre-treatment one;however,there was no clear difference between two post-treatment groups(P>0.05).YGTSS scores were both well-improved by Xifengditantang and Changmaxifengpian,showing an equivalence in the clinical efficacy of these two above-mentioned methods.The after-treament total motor tic YGTSS droppedsome points than the before-treatment groups' scores(P<0.01),but there was no significant difference between the two after-treatment groups(P>0.05).YGTSS scores were both well-improved by Xifengditantang and Changmaxifengpian,showing an equivalence in the clinical efficacy of these two above-mentioned methods.There was an abssolute difference in the scores of vocal tic disorders YGTSS measured between before&after-treaments groups(P<0.05).The vocal tic disorders symptom turned good during the trial of Xifengditantang and Changmaxifengpian medication.However,no disparity was observed between the 2Spost-treament groups(P>0.05).Before and after the treatments,YGTSS traumaticinjury results were compared to each other.A differencebetween these groups were statistically significant as a reduction indentified in post-treatment groups with(P<0.01).Xifengditantang and Changmaxifengpian treatments effected a great change in reducing TD impacts on children daily living behaviours,and the post-treatment traumatic injury scores were fairly equal,though.Due to that assessment,there was no clear difference between the two groups(P>0.05).The total average score of post-treatment main symtomps on 2 groups was smaller than these 2 group pre-treament main symtomps,(P<0.01),but no statistically significant was regconized between the two groups' post-treatment error comparison(P>0.05).The trial showed that Xifengditantang and Changmaxifengpian treatments on TD children with Fengtanraodong syndrome came out with equivalent efficacy.An abstinence symptoms comparison between the pre-&post-treatment groups were implemented,corresponding to a significant difference at(P<0.01),and there was also asignificant difference between these two groups(P<0.01)Xifengditantang treatment improved TCM abstinence symptoms more effective than Changmaxifengpian.The total average score of TCM post-treament symtomps in comparison with pre-treament's showed asignificant difference(P<0.01),also there was a significant difference between two post-treatment groups(P<0.05).Xifengditantang treament improved general TCM symptoms more effective than Changmaxifengpian.After the 4-week treatment,motor tic scores in Xifengditantang group were obviously lower than Changmaxifengpian group's(P<0.05).The effect of Xifengditantang on improving motor tic symptoms was greatly boosted than Changmaxifengpian's efftect.Effectiveness:Xifengditantang curatively controlledthe clinical symtomps of 17 cases,had marked effect on 12 cases,the total effective rate was 59.2%.Meanwhile,Changmaxifengpian curatively controlled the clinical symtomps of 12 cases,had marked effect on 15 cases,the total effective rate was 52.1%in sum up.The clinical efficacy of treating TCM syndromes was measured after trial:Xifengditantang curatively controlled the clinical symtomps of 13 cases,had marked effect on 28 cases,the total effective rate was 83.7%.Meanwhile,Changmaxifengpian curatively controlled the clinical symtomps of 11 cases,had marked effect on 19 cases,the total effective rate was 62.1%.According to these figures,the overall effective rate in Xifengditantang group was significantly higher than Changmaxifengpian group's,witha statistical significance at(P<0.05).Conclusion:?Xifengditantang and Changmaxifengpian are both effective in treating Fengtanraodong syndrome in TD children and well-improved motor tic and vocal tic;?Xifengditantang has more outstanding curative effects than Changmaxifengpian in improving TCM syndromes.In addition,Xifengditantang is markedly effective in alleviating motor tic symptoms thanChangmaxifengpian treatment.
Keywords/Search Tags:Tic disorder, Tourette syndrome, Fengdongtanrao, Xifengditantang, Clinical research
PDF Full Text Request
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