The Study Of The Law Of Compatibility Of Medicines In Warm Cathartic Formula

Objective Combed the historcial of warm cathartic formula and condusion the law of medicial compatibility.In order to apply it effectivily and reasonably in practice.And to provide scientific theoretical basis on relevant experimental research.Method The study use historical timeline for baseline to comb the historical evolution of warm cathartic formula.Taking the 448 warm cathartic formula in Prescriptions of traditional Chinese medicine dictionary and Class of traditional Chinese medicine dictionary as the research object.Using data mining software Spss Clementine 14.0 to study the types of medicines,frequency of drug,Herb pairs,drug groupand mainsyndrome in prescriptions.To discuss the law of compatibility of medicines in warm purgating prescription.Result(1)historical evolution:(1)In pre-qin period the warm cathartic formula under stages in germination.The principal syndrome conclude chest binding syndrome with cold fluid,hypochondriac pain with cold and sudden abdominal pain.The embryonic form of preion compatibility is purgatives medicine combined interior-warming drug.(2)Wei jindynasty,southern and northern dynasty period not only continue to use the former embryonic form but also appear the structure that purgatives medicine combined interior-warming drug and qi-supplementing drug.(3)The development of the sui dynasty and tang dynasty is bigger.The range of principal syndrome expanded qi xue and fluid syndrome like abdominal mass,or retention of phlegm and fluid.The period put forward the idea that the constipation is the one of the principal syndrome by warm cathartic formula.The synergy structure appear the new which is purgatives medicine combined interior-warming drug,activating qi flowing drug,blood-supplementing drug,drug for invigorating blood circulation and eliminating stasis and inducing resuscitation drug.? Song-Jin-Yuan dynasties,eight methods raised by Zhangjinyue enriched throry of warm cathartic formula.The principal syndrome added others like dry choleras or seven types of hernia.The synergy structure added yang-supplementing drugs,astringent medicinal combined with purgatives medicine.?During the Ming and qing dynasties,the principal syndrome and synergy of warm cathartic formula continued to adopt song dynastie's.The apperanceof monograph of discourse on preion provide a basis for theoretical analysis and clinical application about warm cathartic formula.(2)medicinecharacteristics:(1)Warm cathartic formulacharacteristics:1)The top-ten medical classes used in warm cathartic formula following is purgatives medicine,interior-warming medicinal,qi-promoting methodrespiration medicinal,drug for invigorating blood circulation and eliminating stasis,qi-supplementing medicinal,diaphoretic drug,damp elimination drug,reducing phlegm drug,blood-supplementing medicinal,antiasthmatic.2)The top-ten Chinese materia medica used in warm cathartic formula following is da huang,ba dou,rou gui,mu miang,ganjiang,fu zi,bin lang,zhi gan cao,dang gui,ren shen.3)The high frequency couplet medicines and drug group following is da huang combined rou gui,da huang combined bing lang and mu xiang,da huang combined mu xiang,bing lang and rou gui,da huang combined mu xiang,bing langrou gui and dang gui.(2)warm cathartic formulawith badou characteristics: 1)he top-ten medical classes used in warm cathartic formula with ba dou following is purgatives medicine,interior-warming medicinal,qi-promoting methodrespiration medicinal,drug for invigorating blood circulation and eliminating stasis,Poison attack insect to rotten boils medicine,antiasthmatic,diaphoretic drug,reducing phlegm drug,qi-supplementing medicinal and zhi xue medicinal.2)The top-ten Chinese materia medica used in warm cathartic formula with badou following is badou,ganjiang,da huang,mu xiang,rougui,qing pi,fu zi,san leng,bing lang and yuan hua.3)The high frequency couplet medicines and drug group following is ba dou combined gan jiang,ba dou combined da huang,ba dou combined da huang and gan jiang.Conclusion(1)In ancient,the discuss of warm cathartic formula is getting better over time.The synergy structure of warm cathartic formula changes from simple to complex.Physicians of past generations on the basis ofinheriting predecessors' constantly improve.The synergy structure of warm cathartic formula reflect the synergy structure of warm purgative method in Sui-Tang dynasties.(2)The major way of regularity in drug combination of warm cathartic formula is purgatives medicine combined interior-warming medicinal,using qi-promoting methodrespiration medicinal,qi-supplementing medicinal,blood-supplementing medicinal,aromatic damp-resolving drug and drug for invigorating blood circulation and eliminating stasis secondly.The synergy structure in common use of warm cathartic formula with ba dou followed Emergency pill of three Ingredients raised by Zhang zhongjing after the qin and han dynasties.The major way of regularity in drug combination is purgatives medicine combined interior-warming medicinal,using qi-promoting methodrespiration and drug for invigorating blood circulation and eliminating stasis secondly.