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Study On The Clinical Application Of Artemisia Scoparia Waldst Et Kit Decoction In The Treatment Of Chronic Viral Hepatitis B Based On Data Mining

Posted on:2019-03-15Degree:DoctorType:Dissertation
Country:ChinaCandidate:Y J W a n g WangFull Text:PDF
GTID:1314330545469314Subject:Chinese medical science
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Research PurposeVia sorting out the documents on treatment of chronic viral hepatitis type B in recent 15 years in mainland Chin,conclude the usage rule and features of medicine use of chronic viral hepatitis type B clinical treatment by Artemisia scoparia Waldst et Kit Decoction,to lay a foundation for improving the effect of Chinese medicine’s treatment of viral hepatitis type B.Research MethodThis research retrieves,screens,sorts out and collects the main depository and database such as CNKI,ChinaInfo.com,traditional Chinese medicine journal,depository and database,etc.,looks for data in library of Nanjing University of Chinese Medicine and Nanjing Library,and sorts out relevant data on the clinical research of using traditional Chinese medicine to treat chronic viral hepatitis B.It mainly inquires about the above document and literature via retrieving "Artemisia scoparia Waldst et Kit Decoction","chronic viral hepatitis B","traditional Chinese medicine","jaundice",etc.;these documents and literature are all in Chinese.Each thesis’s inclusion standards are screened according to inclusion standards and exclusion standards;only the one that matches chronic viral hepatitis B will be included into the literature research.it retrieves the literature and journal from January 1st,2000 to December 31st,2015,uses Medcase V3.2 data record and mining system,uses enhanced association rule data mining and computation model to mine the data,and uses K-means cluster to compare the relevance of drug use,conduct systematic analysis and conclude the drug use rules.Research ResultsScreen and conclude 29 effective clinical researches of Artemisia scoparia Waldst et Kit Decoction treating chronic viral hepatitis type B,mine the rules and features of disease cause,disease mechanism,the disease and medicine,discover that the modern traditional Chinese medicine practice still uses Artemisia scoparia Waldst et Kit decoction to treat chronic viral hepatitis type B with accumulation of damp heat,there are still 3 types:stagnation of liver qi and spleen deficiency,extravasated blood blocking the channels and stagnation of liver qi;the last three causes,mechanisms and syndromes are related to the evolution of damp and heat or change of disease,the coating on the tongue:the tongue nature is red,the tongue coating is yellow or yellow&sticky,the proportion of rapid pulse and wiry pulse is far greater than 50%,the main reason of seeking medical consultation is abnormal liver function,other clinical symptoms include:rib pain,lack of strength,yellow body,yellow eyes,nausea,poor appetite,yellow urine,abdominal distension and yellow face;the main prescription of Artemisia scoparia Waldst et Kit Decoction is jasmine,Artemisia scoparia Waldst et Kit and rheum officinale,they are the main medicine in clinical treatment,there is no cut,other common compatible medicines include Poria cocos,liquorice,radix curcumae,root of common peony,Rhizoma Atractylodis Macrocephalae and the root of red-rooted salvia,the frequency of appearance is over 30%,the medicine for clearing away heat and toxic materials and clearing damp and promoting dieresis is most common.The dosage of Artemisia scoparia Waldst et Kit is most often 30 g and 20 g,the dosage of Artemisia scoparia Waldst et Kit of 15 g and below is less,the dosage of jasmine and rheum officinale is most often 10 g,the dosage of jasmine and rheum officinale of 15 g,12 g and 6 g is less,there are different experience and opinions of the dosage of Poria cocos,root of common peony and radix curcumae,and the usage of isatis root and Lysimachia christinae Hance is relatively great.Research ConclusionClinically,modern traditional Chinese medicine still uses the ancient classical prescription Artemisia scoparia Waldst et Kit Decoction to treat chronic viral hepatitis type B;the main disease mechanism is dampness and heat,modern traditional Chinese medicine combines the change of disease mechanism of different disease courses,adjusts the selection and use of compatible traditional Chinese medicines,uses Poria cocos as the main compatible traditional Chinese medicine,combines other medicines which can clear away heat and toxic material and clear damp and promoting dieresis,strengthens the function of resolving dampness and clearing heat and reforms the ancient prescription;on the basis of compatibility,using a large amount of Artemisia scoparia Waldst et Kit is recommended by many doctors,the dosage of jasmine and rheum officinale should be added or decreased in accordance with the disease;modern clinical medicine finds that this prescription is effective in treating the abnormal liver function of the patients,it also is effective in treating other accompanying symptoms such as poor appetite,lack of strength,jaundice,etc.;this classical prescription’s medicine dosage is mainly a large amount of Artemisia scoparia Waldst et Kit,the clinical effect is obvious.
Keywords/Search Tags:literature research, chronic viral hepatitis type B, Artemisia scoparia Waldst et Kit Decoction, Artemisia scoparia Waldst et Kit
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