| Objective:Analysis of related literature for flu syndrome study questionnaire and agree with expert,make statistical and analysis flu main syndrome category.The relationship between main TCM(Traditional Chinese Medicine)syndrome type and virus subtype will be presented.At the same time follow-up by telephone partial patients for evaluation outpatient treatment clinical curative effect of influenza.Clear the flu syndrome characteristics of TCM and effect of Proprietary Chinese medicine treatment the flu.Lay a foundation for exploring effective prevention and control of influenza of TCM.Methods:Invite related clinical experts and evidence-based medicine experts to design clinical questionnaire formed "TCM syndrome characteristics of influenza questionnaire"and product software for input data.The clinical research to adopt forward-looking,open mode,supervised and unsupervised combined observational case research method to collect the related information and input clinical information to the collection and analysis system.Using SPSS13.0 software descriptive statistical methods to analyze the general information of patients and frequency analysis of count data.All cases involved the symptom,TCM syndrome and other information for ratio analysis,factor analysis,cluster analysis and regression analysis.Results:Through the study of influenza-like,most patient visit hospital in November 2016 to March 2017.Analysis of 724 patients,456 cases female(62.98%),"Married" 536 cases(74.34%),living in the home 676 cases(93.50%).Induced by "catch cold" 285 cases(54.70%).Report the sudden onset of 627 cases(87.94%).706 people have complained of as a fever(97.51%).Most early symptoms with fever,there are 302 cases 171 cases(41.71%).Systemic symptoms are cold 492 cases(68.05%),sore and ache 541 patients(75.03%),headache 517 cases(71.61%),fatigue(82.87%).Local symptoms include runny nose 440 cases(60.77%),cough symptoms 588 cases(81.22%),pharynx itching 435 cases(60.08%),dry mouth 544 cases(75.14%).TCM syndrome types Fengrefanwei Zheng 208 cases(28.81%),Fenghanshubiao Zheng 107 cases(14.82%),Biaohanlire Zheng 404 cases(55.96%),Shireneiyun Zheng 3 patients(0.42%).In flu H1N1 women 80 cases(70.18%),married 91 cases(79.82%),living in the home 107 cases(93.86%).Catch a cold for disease 52 cases(45.61%),27(23.68%)of patients with high fever.Patients with sudden onset of 101 cases(89.38%).Complained of fever reported 112 cases(98.2%).Systemic symptom clinical manifestations:evil cold in 76 patients(66.7%),sore and ache all over 96 cases(83.9%),85 cases(74.6%)are headache,fatigue 102 cases(89.5%).Local symptoms include:76(66.7%)cases of sputum,75(65.8%)cases of pharyngeal itching,63 cases(56.8%)sore throat,runny nose 75 cases(65.8%),cough 109 cases(95.6%),pharyngeal hyperemia 63 cases(51.8%),dry mouth 92 cases(80.7%),and thirst 85 cases(64.9%).In H3N2 influenza the female 96 cases(64%),married 120 cases(80%),living in the home 138 cases(92%).58 cases(38.67%)due to catch a cold for disease.Patients with sudden onset 126 cases(84%),Complained of fever reported 149 cases(99.3%).Early symptoms of bad cold 33 cases(22.3%),fever 56 cases(37.8%),sore throat 20 cases(13.5%).Systemic symptom of significant clinical manifestations:evil cold in 99 patients(76.0%),sore and ache all over 107 cases(71.3%),116 cases(77.9%),fatigue 125 cases(83.3%).Local symptoms:sputum 96 cases(64.4%),pharyngeal itching 100 cases(66.7%),sore throat 96 cases(64.9%),runny nose 110 cases(73.3%),cough 127 cases(84.7%),pharyngeal hyperemia 96 cases(64.9%),dry mouth 108 cases(73.0%),and thirst 99 cases(67.8%).In B flu women 86 cases(61.87%),married 93 cases(67.39%),living in the home of 130 cases(93.53%).Because of catch a cold for disease has 52 cases(37.41%).Sudden onset of flu patients in 122 patients(88.41%).Complained of fever reported 133 cases(95.7%).Early symptoms of bad cold 31 cases(22.8%),fever 46 cases(33.8%),sore throat 20 cases(14.7%).Systemic symptom of significant clinical manifestations:evil cold in 104 patients(74.8%),sore and ache 105 cases(75.4%),headache 101 cases(73.2%),fatigue 113 cases(81.3%).Local symptoms are:sputum in 92 cases(66.2%),96 cases of pharyngeal itching(69.1%),83 cases(61.0%)sore throat,runny nose 91 cases(65.5%),cough 127 cases(91.4%),pharyngeal hyperemia 83 cases(61.0%),113 cases(81.9%)dry mouth,and thirst 107 cases(77.5%).The H1N1 flu TCM syndrome type distribution Fengrexibiao Zheng 24 cases(21.1%),Fenghanshubiao Zheng 11 cases(9.6%),Biaohanlire Zheng 77 cases(67.5%),Shireneiyun Zheng 2 cases(1.8%).The H3N2 flu TCM syndrome type distribution Fengrexibiao Zheng 35 cases(23%),Fenghanshubiao Zheng 17 cases(11.3%),Biaohanlire Zheng 98 cases(65.3%),Shireneiyun Zheng 0 cases(0.0%).The B flu TCM syndrome type distribution Fengrexibiao Zheng 29 cases(21.0%),Fenghanshubiao Zheng 21 cases(15.2%),Biaohanlire Zheng 88 cases(63.8%),Shireneiyun Zheng 0 cases(0.0%).183 cases in 724 cases reported their self-medication types including antibiotics 116 cases(63.39%),only use proprietary Chinese medicine 12 cases(6.56%),only taking antifebrile 11 cases(6.01%),the rest are two or three drugs combination of 44 cases(24.04%).Not use western medicine 22 cases(7.53%),only use antipyretic 52 cases(17.81%),using only cough remedies of 4 cases(1.37%),only use of antivirals 34 cases(11.64%),using only the phlegm drugs 9 cases(3.08%),only use antibiotics 11 cases(3.77%),only for your nose and sneezing in 4 cases(1.37%).Use two or more drugs include the antifebrile 127 cases(43.49%),use two or more drugs do not contain the antifebrile 29 cases(9.93%).Use the Chinese medicine correct 170 cases(47.2%),not correct 175 cases(48.6%),both of the two group defervescence time,course and clinical curative effect had no significant difference.Conclusion:Influenza-like and influenza cases visits peaked in 2015 winter to 2016 spring.Mostly women,married and living in the home crowd.Considering influenza-like patients related with climate and environment.And influenza symptoms mainly systemic symptom like evil cold,sore and ache,headache,fatigue and the upper respiratory tract symptoms like sore throat,cough,phlegm.Different virus subtype with slightly different clinical symptoms for example and influenza A virus pathogenic fever,systemic symptom and pharyngeal symptom heavier,but influenza B virus pathogenic more modest,and gastrointestinal symptoms are heavier.TCM syndrome types of different influenza virus mainly Biaohanlire Zheng,but Biaohanlire Zheng in influenza patients significantly higher than that of patients without flu.Through follow-up outpatient clinic patients,we found that patients at the beginning of the illness have self-medication most is antibiotics.Outpatients with early disease was given antipyretic analgesics,antiviral and Chinese medicine,after the treatment the symptoms of fever,systemic symptom and local symptom significantly improved.This study suggests us take attention to monitoring of influenza-like cases with different populations and TCM syndrome ty pes should be further clear in influenza patients,as far as possible select the appropriate Chinese medicine treatment influenza needs further attention. |
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