Clinical Study On The Theory Of Treating Upper Airway Cough Syndrome By Zhang Zhongjing's Expelling Phlegm Method

Background:Upper airway cough syndrome(UACS)is one of the common causes of chronic cough in clinical practice.Patients show cough,stuffy nose,throat itching,post nasal drip and other similar symptoms.But long,frequent,severe coughing will affect the patient's work and life.This topic is the study of the application of Zhongjing's method of phlegm elimination in the treatment of airway cough syndrome,aiming to contribute to the treatment and health care of these people.Objective:After treating patients airway cough syndrome for a long period,my PhD Supervisor found that both in the treatment method or the use of the formula are in line with the "Treatise on Cold Pathogenic and Miscellaneous Diseases".Thus,through the diagnosis and treatment of upper airway cough using the syndrome differentiation and treatment method of Chinese Medicine,also,by research and induction,to find the significances of upper airway cough syndrome's pathogenesis,syndrome patterns,this research wishes to better guide the clinical diagnosis and treatment in this area.In addition,patients with upper airway cough syndrome in Nanjing were compared with patients in Singapore in order to find out the similarities and differences between them.Methods:Clinical investigation to120 patients from the Mingji Hospital in Nanjing was carried out from March 2015 to June 2016.Analysis of clinical data,and based on syndrome differentiation of Chinese Medicine:(i)the clinical applications were analyzed;(ii)the clinical application and pharmacology of formula used to treat airway cough syndrome were analyzed and summarized.These were done with the aim to provide a more comprehensive theoretical basis for clinical treatment.Results:By analyzing the characteristics of patients with upper airway cough syndrome,it is found that its causes,syndrome differentiation and treatment and other aspects is rather consistent with the phlegm elimination method as recorded in Zhang Zhongjing's "Treatise on Cold Pathogenic and Miscellaneous Diseases".This finding can consolidate the efficacy of treatment,improve the conditions of the patients,also,reduce the incidence and recurrence rate of the disease.Conclusion:In patients with chronic cough involving the spleen,liver,kidney and other organs,the treatment process need to take into account the lungs and other related Zangfu.In addition,my PhD Supervisor also attaches great importance to syndrome differentiation.As the main pathological factor of upper airway cough syndrome is phlegm,thus in the treatment,herbs which eliminate phlegm,relieving cough and pacifying asthma accounted for up to 86%of all herbs in the compound formula.Commonly used herds are Fritillaria,Campanulaceae,Pinellia and Citrus Aurantium.In addition,the upper airway cough syndromes also involve the nose and throat and other diseases.Major symptoms are cough,cough up phlegm,post nasal drip,but also accompanied by itchy and throat mucus adhesion.Therefore,herbs pair such as Angelica and Magnolia liliflora is used for some of the nose and throat paralysis and other diseases,for relieving exterior cold,also unblocking the nasal orifices.There are also exterior relieving herbs which both governance throat paralysis,throat itching and other symptoms,such as Arctium,Campanulaceae,Mint and so on.Compound formula for treating upper airway cough syndrome can improve the clinical symptoms of upper airway cough syndrome.They are can be widely applied with great effectiveness.It is hoped that this dissertation of the upper airway cough syndrome and the prescription of the compound prescription can provide new methods and ideas for the treatment of the upper airway cough syndrome from the perspective of etiology and pathogenesis,syndrome differentiation and medication.In addition,after comparing the patients with upper airway cough syndrome in Nanjing with patients in Singapore,it was found that the region,the climate,the environment,the diet,or the living habits directly affected the syndrome patterns of the upper airway cough syndrome.For example,Singapore patients with "phlegm dampness accumulation in lung",account for 41.3%of overall.In comparison,Nanjing patients with "phlegm dampness accumulation in lung",only account for 2.5%.This is mainly due to:(?)Singapore is surrounded by the sea,(?)the high moisture content of the tropical countries;(?)many are residents of living long-term in air conditioned environment.In the diet,Singapore residents love to drink cold drinks,and eat fried and spicy food.As many patients have deficiency in the Spleen functions,coupled with improper diet,which help in the development of wet phlegm,these factors resulted in "phlegm dampness accumulation in lung".Whenever the weather/temperature change slightly,coupled with the lowering of self immunity,it is particularly easy to be affected by cold evil and wet evil,causing airway cough syndrome.