Professor Ding Yongsheng, A Famous Chinese Doctor In The Country, Studied The Regulation Of Diarrhea

Objective:Spleen and Stomach disease has a long history in Traditional Chinese Medicine (TCM), origined of Inner Canon of Huangdi. Spleen-Stomach theory of Li Dongyuan and his apprentice was founded Jin and Yuan Dynasty, and physicians of later generations have enriched and developed the Spleen-Stomach theory of TCM. Professor Dai Yongsheng, as the national old heritage of Traditional Chinese Medicine workshop instructor, is the fifth batch of TCM academic experience inheriting the job instructor and the first session of Famous Old Traditional Chinese Medicine in Guizhou Province. He is also professor and director of Chinese medicine practitioners. He has healed patients for nearly 50 years and has rich experience. Not only he inherits the classical and clinical use, but also he is good at syndrome differentiation, drugs and prescription, especially for the spleen and stomach disease of TCM. Thus to inherit and carry forward famous TCM doctors academic thoughts, this study is going on in academic thoughts of the law of syndrome differentiation and treatment of diarrhea for professor Dai Yongsheng.Method:Through clinical study of four traditional clinical diagnosis, collecting and analyzing the clinical case of diarrhea, reading and clearing up his dissertation and writings of academic thoughts and clinical experience, the use of modern data mining techniques and the assistant platform of inheritance of traditional Chinese medicine system software (V2.5) analyze association rules etc. Analyze and generalize the data of clinical diagnosis and treatment of diarrhea in clinical medical prescriptions for professor. Summarize dialectical characteristic, prescriptions and medication rules for Professor Dai Yongsheng.Observe the effect of Sijunzi Tang combined with Pingwei San to cure functional diarrhea with damp abundance due to splenic asthenia means to further excavate the academic thoughts of Professor Dai and his treatment of diarrhea from the perspective of clinical research.Result:Assistant platform of inheritance of traditional Chinese medicine system software (V2.5) have finished processing Professor Dai in both diagnosis and treatment of diarrhea due to prescription of 180 cases. Through data mining and refining analysis,21 main types of treatment of diarrhea for professor Dai were found. Its main medication is to reinforce qi or dissipate dampness. Based on associated analysis of common "couplet medicines" and combinations, we can find "couplet medicines" being used more than 55 times and 20 combinations, such as frequency of Poria and Radix Glycyrrhizae is about 122 times, frequency of Poria and Rhizoma Atractylodis Macrocephalae is 99 times, frequency of Rhizoma Atractylodis Macrocephalae and Radix Glycyrrhizae is 96 times, as well as frequency of Radix Adenophorae Tetraphyllae and Poria is 94 times etc. Among them, commonly used medicines are Radix Adenophorae Tetraphyllae?Poria?Rhizoma Atractylodis Macrocephalae?Radix Glycyrrhizae etc., all of which are warm in four natures of drugs and sweet in five tastes. The core portfolio analysis based on entropy clustering of complex systems evolves a total of 10 core combinations which include 3-5 herbs. The number of new prescriptions of treating diarrhea based on hierarchical clustering are 5, each of them includes 4-5 herbs.Through summarizing and analyzing 180 clinical cases of professor Dai, a few features are concluded, such as the unique of dialectical method, the individuality of clinical typing, the relationships between theory of five elements and examination and therapy and the combination of classical prescription.It is shown in clinic that Professor Dai apply Sijunzi Tang combined with Pingwei San to cure diarrhea and his curative effect of therapy group is up to 90% and control group is 73.3%. The effect of therapy group is obviously higher than control group (P< 0.05). A month later, the patients are followed up. Among the therapy group,24 of them are interviewed and 3 of them recur and its relapse rate is 12.5%. Among the control group,18 of them are interviewed and 8 of them recur and its relapse rate is 44.4%. It has statistical significance via chi-square test between the above groups and relapse rate of control group is higher than therapy group.Conclusion:Professor Dai Yongsheng believes the main pathogenesis is qi asthenia or dampness. Its main medication is to reinforcing qi or dissipating dampness, which usually include Radix Adenophorae Tetraphyllae?Poria?Rhizoma Atractylodis Macrocephalae?Radix Glycyrrhizae etc. Many kinds of crossing applications for syndrome differentiation are more suitable for clinic. The combination of prescriptions enlarges the original formula. To inherit and sort out the academic ideas of professor Dai for his empirical prescription is to record his clinical samples and to inherit his clinical experience, and to further dig it. It is better for researching and developing new medicine to combine traditional and modern methods, which fully reflects features and advantages and is also inheritance and creation. It is proved that professor Dai gain better therapeutic effect with the combination of prescriptions for diarrhea and with no evident side effects, which deserves wide application in clinic.