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Correlation Between Syndrome And Blood Gas Analysis In Common Lung Diseases In Xiongpi

Posted on:2015-01-04Degree:DoctorType:Dissertation
Country:ChinaCandidate:X Y ZongFull Text:PDF
GTID:1264330428471338Subject:Traditional Chinese Medicine
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Modern medicine considers XiongPi as the Secondary diagnosis of PiMan, Textbooks like "Chinese Medicine Textbook of internal medicine" all carrying the same point of view. Because of its rarely came to be a separated disease, XiongPi often ignored by clinical diagnosis. But in clinical practice, patient encounters the chest discomfort symptoms, doctors will have to taking account into its treatment. And all the diseases associated with symptom of chest fullness, can also be the same disease without chest fullness. This phenomenon also shows that although XiongPi often associated with other diseases, but it has its own independent pathogenesis. Therefore, in clinical practice,XiongPi should be put as an independent disease to treat. Only by fully understanding Xiongpi as an independent disease, etiology and pathogenesis profoundly understand, can we be better in clinical practice.TCM’s essence lies in syndrome differentiation and treatment, to accurately understand the syndrome is a prerequisite to obtain clinical curative effect, so this study is in order to findout XiongPi’s definition, diagnosis, pathogenesis and therapeutic methods by literature study, clear XiongPi as an independent diagnosis of internal medicine diseases. And by retrospective clinical study combined with modern statistical methods to explore the elements of syndromes and syndromes of XiongPi distribution rule, and the correlation between physicochemical examination results and syndromes of XiongPi.According to34ancient literatures,we manage to determine the definition of XiongPi:XiongPi is composed of the evil invasion, excessive drinking, eating unclean food, emotional disorders; hobby and the job environment is not good, maladjustment of work and rest, chronic disease, and treatment failure or mistreatment and other factors, resulting in the deficiency of vital qi, Yin and Yang Qi and blood disorders, stranded in chest air congestion, cold, wet, dry, fire, phlegm, blood stasis, turbidity and other bad factors resistance disturbance, chest Qi of yin and Yang choke, abnormal movements caused by blocked uncomfortable tightness in the chest, breathing is not smooth, there was no thoracic shape change, there was a block in the feeling, but no pain. Make further efforts,we also try to find out the etiology, pathogenesis, treatment, prescription of XiongPi.Analysis of the main clinical symptoms "the chest fullness" of XiongPi, we discover the close relationship between XiongPi and lung disease, and blood gas analysis, determines the basic direction of the research.Research part: Purpose: Through the analysis of117cases of diagnostic data, to explore the distribution of syndrome elements and syndrome of XiongPi, and further to explore the correlation between common syndromes of XiongPi and blood-gas analysis results.Method: According to the method of clinical epidemiology cross-sectional study, we collected the four diagnostic information from patients meet the acquisition of XiongPi of Dongzhimen Hospital Department department of respiration,using the application of Epidata3.0software to establish a database, using SPSS24.0software for statistical analysis. The general clinical data using descriptive statistical analysis on frequency, percentage representation; Chinese medical information application of principal component analysis factor extraction combined with clustering analysis, theoretical peak test are analyzed based on rough set. Type of syndrome and blood-gas analysis results by Logistic regression analysis.Results:1.Distribution of syndrome elements:with clustering analysis by factor extraction, there are20common factors.Consulting manually identify, that XiongPi related syndrome elements mainly include6position syndrome elements, respectively is:the lung, heart, liver, spleen, kidney, stomach;7quality syndrome elements, respectively is:deficiency of Qi, Yang and Yin, qi stagnation, phlegm, dampness, fire.2. Distribution of syndromes:Firstly by a simple reduction in accordance with the principle of minimum risk decision value to determine the number of target poly peak is4. After the data into the Nelson model checking formula to poly Feng, altogether obtains3common types, respectively is:"the lung spleen qi deficiency and phlegm dampness syndrome","liver qi stagnation syndrome","Yang deficiency of the spleen and stomach damp depression transforming into fire".3.Study on relationship between the common syndromes and blood-gas analysis results:make standard of the above3common types, rescreening all117cases,43cases were selected, which conforms to the lung and spleen deficiency phlegm syndrome18cases,11cases with liver and stomach qi stagnation,14cases with Yang deficiency of the spleen and stomach, wet fire retarding syndrome. Studying the blood-gas analysis results of the43cases, in order to observe syndromes from the perspective of the blood-gas analysis. Consider the three types of XiongPi syndrome differentiation of traditional Chinese medicine as the dependent variable, pH, P02, PCO2were the independent variables, using multiple linear Logistic regression, ordinal Logistic regression analysis, according to the regression equation, deduce syndrome cases in blood-gas analysis results in oxygen partial pressure offset based bias in the lung spleen deficiency phlegm dampness and greater possibility. Syndromes mainly pH shift in blood-gas analysis results in the case of bias in the liver qi stagnation syndrome is more likely; possibility for blood-gas analysis results in the partial pressure of carbon dioxide offset based case bias in the spleen and stomach Yang deficiency and phlegm stagnation of fire more.
Keywords/Search Tags:XiongPi, symptom, syndrome, syndrome element, blood-gasanalysis, rough set
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