| Rapid prototyping was a manufacturing technology which could rapidly make object with laminated manufacture method according to 3D design, this technology intergrated many subjects such as mechanical engineering, computer technology, numerical control technology and material science. It was a new kind of advanced manufature technology and would have a significant imapct on production models and people’s life models. Because of the special principle of protoyping and its advantage on irregular surface manufacturing, this technology was appropriate for biomedical model such as human bones.Computer modeling and simulation were important methods for biomechanical analysis of human bones. How to achieve the purpose for improving the operation accuracy, shortening the operation time, optimizing operation program and reducing pain of patients with existing technologies to make a biomechanics analysis effectively in the actual human mandibular occlusion, has become the problem demanding prompt solution of mandibular biomechanics simulation analysis.This subject supported by the relevant project fund, the cross-disciplinary of advanced manufacturing technology and biomedical engineering was researched. Some key techniques of rapid prototyping manufacturing technology-based human defect mandibular reconstruction and biomechanics analysis were made of modeling, simulation analysis and clinical research study with adopting rapid prototyping manufacturing and computer modeling and simulation technology to provide important reference for its structure optimization, clinical operation plan scheme and design. At the same time, network manufacturing of rapid prototyping was researched and realized which could promote the development of this technology. The main research contents of text as follows:(1) A 3D visiulation system was developed based on reverse engineering. This system was develpoed on VC++6.0 and OpenGL tookits. It could make many virtual operations such as rotation, translation and cutting of human bones, and execute the 3D reconstruction from 2D CT datas. Doctors could make accurate operation plan with the help of this system.(2) Subject adopts the personalized and multi-platform collaboration modeling technology platform for specific patients. With the problems of implanting titanium plate’s standardization and mismatching in the process of traditional mandible reconstruction surgery, researched the mandible of specific patients titanium plate individuation modeling method, established mandible titanium plate personalized model, achieved the purpose of optimal design personalized titanium plate 3D model. With the fatigue damage in the process of using titanium plate, to titanium plate for fatigue simulation analysis, optimization titanium plate structure, so as to improve the service life of titanium plate.(3) Adopting the human mandible FEA modeling method based on the reverse engineering CT data, studied and established the original tumor resection patients with mandible, reconstruction after the implant body mandible distraction and implanted the FEA model method. And performed a variety of mandible model in different load cases biomechanical analysis using bone biomechanical and FEM integrated simulation technology based on this model, so as to optimize the design scheme of dental implants, improve the precision and lower the surgical risk.(4) With the coorpation of hospital, the results of this subject were applied into clinical test. The rapid prototying were applied on a lot of researchs of medical records such as organism prosthesis manufacturing, lower jawbone direction of clinical operation, skull damahe repairment. By clinical verifications and constrastive analysis, the rapid prototying that used on upper jaw bone could solve the collapse facial profile effictively. In the surgery of lower jawbone and skull defect, five medical records were used to proof that the rapid prototying technology could decrease the operation time to 2 hours. At the same time, it also could improve the surgical percision, relieve pations’s pain and reduce the risk of the operation.(5) Adopting the remote diagnosis of rapid prototying methods, according to the cuurent situation of medical resource overbalance, a system whth technical service, remote diagnosis, task processing was developed. This system could intergrate the dispersive rapid prototying resources and medical resources and give the less developed areas more advantage resources by internet. The hospical of remote area could impliation some difficulte surgery by the help of remote diagnosis and minimize operation time as well as improve the success rate. |