Experience Summary And Clinieal Study On Professor Fang Xianming Treating Coronary Heart Disease

Fang Xianming, one of National Instructors of Aceademic Experi-ence Inherit of Old Chinese Medieine ExPerts, has engaged in teaching, elinic and research work of "Chinese Medieine Physicians" more than30years and accumulated rich clinical experiences. He is expert intreating cardiovascular and digestive diseases, and has unique opinions in diagnosing and treating of seasonal and stubborn diseases as well, forming his own academic style. The Project sums up the academie thoughts and clinieal experiences of Professor Fang Xianming treating Coronary heart disease based in pathogennesis obtained through differentiation of symptoms and signs by collecting and analyzing his clinical cases and reading and sorting out the dissertations and works relatively.Coronary Heart Disease(CHD) is a corramon cardiovaseular disease. The disease occurs following coronary atheroselerosis which causes lumen of blood vessel narrow, followed by such clinical symptoms as insuffieieney of blood supply from coronary artery, aeute myoeardial infaretion, transient isehemia, and anoxia. The disease belongs to the thoracic obstruetion in traditional Chinese medieine. This dissertation addresses some aspects indetails about coronary artery disease treated with Chinese medicine.1. To discuss the etiology,pathogennesis, dialectical grouping, and treatment method of Coronary Heart Disease.2. To sums up the academie thoughts and clinieal experiences of Professor Fang Xianming of the etiology, pathogennesis, dialectical grouping, and treatment method of Coronary Heart Disease.3.Clinical symptom researchObjective:To approach the relationship between Coronary Heart Disease and Vulnerable plaque of action of treating Coronary Heart Disease of Spleen deficiency due to stagnation of liver qi by observing therapeutic efficacy of Tiaozhi Granule.Method:Selection of patients based on proposed criterions. In the researeh,50Patients of Coronary Heart Disease are aceidenially chosen. Those are divided into2groups:Tiaozhi Granule and control one. Each consists of25patients. Clinieal symptom studies are implemented in inspecting:cardiogrma, the level of clinical symptom improvement, high-sensitive C-reactive Protein(hs-CRP), Fibrinogen (Fg), carotid intima-mediathiekness (IMT), platelet parameters and Oxidized low density lipoprotein before and after treatment. To study on relationship between change of LDL-C、Fg、CRP、IMT and Vulnerable plaque of coronary heart disease.Result:1. LDL-C、Fg、CRP、IMT may beassociated with CHD.2. Tiaozhi Granule group and control group have obvious difference of LDL-C、Fg、CRP、IMT before and after treatment, after treatment all were signifieantly lower, difference was statistieally signifieant (P<0.05).3.Two groups have obvious difference of LDL-C after treatment, Tiaozhi Granule group were signifieantly lower, difference was statistieally signifieant (P<0.05). Two groups have no obvious difference of Fg、CRP and IMT after treatment, difference was no statistieally signifieant (P>0.05).3. Two groups have no obvious difference of platelet parameters before and after treatment, and have no obvious difference after treatment (P>0.05).Conclusion:LDL-C、Fg、CRP、IMT may beassociated with CHD. There was obviously correlationin the level of seveirty of coronary artery disease. Using Tiaozhi Granule for Angina Pectoris treatment clearly helps improvement of clinieal symPtoms, speeds up Physicochemical index, forecasts relpase of nagina peetoris.