| Objective:To trace the academic origin of Professor YAN Xiao-ping, who was one of the4th batches of national famous senior TCM doctors. To arrange and study the academic thought and clinical experiences of teacher YAN Xiao-ping. To study the efficacy and safety of Gubitong recipe which was a experience prescription treating osteoarthritis made by teacher YAN.Methods:in the aspect of theories and clinical experiences summary:using methods of studying classical books and arranging literatures, the academic thought and clinical experiences of teacher YAN were summarized, arranged and refined. In the aspect of clinic study:using the methods of prospective, random, positive medicine in control,120osteoarthritis patients were arranged in two groups:the treatment group was treated with Gubitong recipe, the control group was treated with Glucosamine hydrochloride. The observation contents included patient’s pain degree, joint stiffness, joint movement dysfunction, WOMAC, clinic syndromes, the whole assessment of patients and doctors. The laboratory tests included:ESR, CRP, the blood, urine, liver and kidney function tests. The side effects were recorded during the treatment periods. All these were recorded in advance of the experiment and after it respectively. In the Gubitong recipe treatment group, all patients were divided into kidney deficiency with cold-dampness invading syndrome and kidney deficiency with heat-dampness invading syndrome, the patients with these two syndromes were compared with the control group in each aspects, including patient’s pain degree, joint stiffness, joint movement dysfunction, WOMAC, clinic syndromes, the whole assessment of patients and doctors, ESR, CRP, the safety tests, the side effects test and so on.Results:in the aspect of theories and clinical experiences summary:from the academic thought of treating Bi syndrome, we could deem that the major academic origin of teacher YAN was originated in the ancient classics books, JIAO Shude academic experience and own clinic experiential accumulation. In concretely speaking, the origin of teacher YAN reflected as the road of famous TCM doctors, the roads of medical inheritance, the roads of exploration and innovation. Teacher Yan had advocated that’from clincal experience, back to clincal experience’in studying TCM, which is said that we should study the TCM Calssics, expecially’the Canon of Internal Medicine’,’treatise on febrile diseases’,’synopsis of golden chamber’,’Item Differentiation of Warm Febrile Diseases’,’wen re jing wei’,’ben cao cong xin’and so on. In the course of studying, we could see that the academic thought of teacher Yan in treating Rheumatology were from the TCM Calssics, for example, teacher Yan thought that the main point in treating rheumatology included tonifying liver and kidney,expelling wind and dampness, adjusting ying and wei, the principle in treating rheumatology is cold syndrome and heat syndrome. In summarizing the academic thoughts of professor Jiao, teacher Yan had pointed out that the academic thoughts of professor Jiao including four necessities, five poinpoints, creating wang bi syndrome, reachering xin bi syndrome, developing axis therory and so on. On the basis of professor Jiao, teacher Yan had advocated many new therories, as the origin of da Iv, the syndrome differentiation and treatment of da lv, advancing the theories of according channel sites in Syndrome Differentiation and Treatment of rheumatology. In the treatment of osteoarthritis, teacher Yan had many unique thoughts in comparing with other doctors, as the knowledge of pathology, pathogenesis, Syndrome Differentiation and Treatment, internal treatment of TCM, external treatment of TCM, synthesizing treatment and so on.In the aspect of clinic study:after the treatment, WOMAC and the global assessment of patients and doctors had decreased, and had remarkable differences. Compared to the control group, in the treatment group, the improvement of WOMAC had remarkable differences, the usage amount of NSAIDs was less, and had remarkable differences, the lever of ESR and CRP had no differences. In two groups, the adverse effects, as the blood, urine, liver and kidney function tests, did not show differences in before and after treatment.Conclusion:in the aspect of theories and clinical experiences summary:in the course of arranging and studying the academic thought and clinic experience of teacher YAN Xiao-ping, I had10outcomes:(1) advocate one theory and two concep(?): the cold and heat synopsis theory, balance concept and tendency concept. The principles of cold syndrome and heat syndrome must base on a basic fundamental, which is tonifying liver and kidney, expelling wind and dampness. In treating rheumatology, the methods of "expelling wind, cold and dampness" and "expelling wind, heat and dampness" would be used respectively. Besides, the internal treatment and external treatment would be used intergrated;(2) emphasize the importance of the differentiation symptoms and signs from Zang-Fu and he method in it, in other words, coordinating the function of Zang and Fu;(3)5consistem ring TCM unique remedy;(4)integration, intensification ana continuum remedy,(5) regard differentiate syndrome following channel and meridian, which supply the differentiation syndrome from Zang-Fu Zang-Fu;(6) Preventive Treatment of Disease academic thought-Bi syndrome which would be Wang Bi;(7) the necessary method for Strengthening Healthy Qi to Eliminate Pathogens-coordinating Ying Qi and Wei Qi;(8) motivate the blood and dredge channel-a method should be used in rheumatic disease all the way;(9) an important aspect in treating rheumatic disease-ascending Yang Qi of spleen and stomach, protecting spleen which is the origin of the acquired constitution;(10) TCM useful technique for treatment, diagnosis and treatment regimen. In the aspect of clinic study:Gubitong recipe had the function of easing the pain and stiffness symptom, of improving joint dysfunction, it was a safe and effective prescription role in the treatment of knee osteoarthritis. |
PDF Full Text Request