| Objective:Throught observing the Epidemic encephalitis b patients in the Midwest of china, we can explore the Epidemiological characteristics, including geographical distribution, Season distribution, and the crowd distribution to distribution. Understand the epidemic disease patterns, especially the transmission way and easy feeling crowd, so we can provide material basis For Epidemic encephalitis b prevention.analyze the characteristics of The Midwest regions Epidemic encephalitis b from etiology and pathogenesis; analyze its clinical characteristics from clinical classification of traditional Chinese medicine and sickness, providing reliable basis for clinical treatment.Methods:(1) We Conduct Research in infectious disease hospitals of Hubei、Chongqing. Guiyang. Sichuan. Ensure the source of the cases.(2) The research object:Epidemic encephalitis b patients. Inclusion criteria:Accord with the health ministry 《The epidemic encephalitis b diagnosis standard》diagnosis; The Epidemic encephalitis b IgM virus antibody is positive. Exclusion standard:The Epidemic encephalitis b IgM virus antibody is negative. Not serum or spinal fluid test.(3) Laboratory test:Mainly the serologic test. Use the immunof luorescence or E LISA method to detect blood or of the viral antigen cerebrospinal fluid.(4) Research methods:According to the patient of the cases, and CRF form, Fill in "epidemic encephalitis b history questionnaire ", including Patients basic situation、diagnosis、Hospitalization and discharge time、Typical symptoms、Signs and Symptoms、TCM syndrome differentiation. The hospital recovery, and so on.Results:(1) Epidemiological characteristics:We collected296cases, the patients attacked Epidemic encephalitis b concentrated in the7,8,9three months. Male patients in152,144patients with women, the sex ratio are1.06:1. Children under the age of five years old are105cases, children of6-10years old are146cases, and children more than10years old are45cases.294patients had n immune history or immune history. There were233patients from the countryside. Their living environment was basic, without any products measure.(2) Syndrome Differentiation Classification:In2010, we Collected116epidemic encephalitis b cases. Among them, Random58cases of control group, Queue the team58cases. Du yun fei wei Classification was28,Du shun nao luo was30,Du xian xin bao was58. In2011, we Collected180epidemic encephalitis b cases. Among them, Random90cases of control group, Queue the team90cases. Du yun fei wei Classification was46,Du shun nao luo was44,Du Xian xin bao was90. (3) Clinical Symptoms:Main observation sickness respectively are:294cases of fever (99.32%)、Headache112cases (27.84%)、 vomiting63cases (21.28%)、convulsive90cases (30.41%) Consciousness obstacle179cases (60.47%)、respiratory abnormal4cases (1.35%). All of the patients had fatigue, Nacho symptoms.219(73.99%) of the patients had meningeal stimulation performance,55cases (18.58%) patients brine levy positive,79patients (26.69%) patients neck stiffness,65patients (21.96%) patients with hyperthyroidism tendon reflex.(4) Clinical Curative Effect:In2010Of the randomized control group, the treatment group cure rate is100%; the control group cure rate is88.89%, the recovery rate is11.11%. In queue the team, the treatment group cure rate is88.46%, the recovery rate is11.54%; the control group cure rate is78.13%, the recovery rate is18.74%, the mortality rate is3.13%. In2011Of the randomized control group, the treatment group cure rate is100%; the control group cure rate is87.80%, the recovery rate is12.20%; In queue the team, the treatment group cure rate is86.50%, the recovery rate is9.30%, the mortality rate is4.65%; the control group cure rate is76.60%, the recovery rate is14.89%, the mortality rate is8.51%.(5)The Three Main Symptoms:In2010Of the randomized control group, The treatment group temperature drops to normal time, average was conscious, average ease twitching, average hospitalization time time respectively are (4.34±1.18) days、(4.66±1.21) days、(3.87±1.16) days、(20±2.15) days. The control group temperature drops to normal time, average was conscious, average ease twitching, average hospitalization time respectively are (6.26±1.27) days.(7.58 ±1.04) days、(6.21±1.08) days、(28±2.34days.In2010Of the queue the team, The treatment group temperature drops to normal time, average was conscious, average ease twitching, average hospitalization time respectively are (5.76±0.24) days、(6.04±1.39)days、(2.87±1.36)days、(23±1.18) days。The control group temperature drops to normal time, average was conscious, average ease twitching, average hospitalization time respectively are (8.74±1.04) days、(8.73±1.54) days、(5.47±1.63) days、(29±2.09) days.In2011Of the randomized control group, The treatment group temperature drops to normal time, average was conscious, average ease twitching, average hospitalization time respectively are (4.42±1.08) days、(4.59±1.12) days、(3.84±1.30) days、(17±2.04) days. The control group temperature drops to normal time, average was conscious, average ease twitching, average hospitalization time respectively are (6.13±1.43) days、(7.53±1.16) days、(6.11±1.24) days、(25±2.75) days.In2011Of the queue the team, The treatment group temperature drops to normal time, average was conscious, average ease twitching, average hospitalization time respectively are (5.66±1.27) days、(5.94±1.45)days、(2.84±1.22)days、(20±1.21)days。The control group temperature drops to normal time, average was conscious, average ease twitching, average hospitalization time respectively are (8.53±1.11) days、(8.66±1.75) days、(5.51±1.15) days、(29±1.54) days.Conclusion:(1) the patients attacked Epidemic encephalitis b concentrated in the7,8,9three months. Patients mainly came from rural (especially mountain) scattered children; their living environment was basic, without any products measure. Epidemic encephalitis b crowd of mainly concentrated in children were under the age of10, a male gender a little was more than women, Most of the patients without Epidemic encephalitis b vaccination history or YiNao vaccination history was unknown(2) The cases with du Xian xin bao type proportion is the largest, following by du shun nao luo and du yun fei Wei. Fever, convulsions, consciousness obstacle are the three important symptoms, Fever was almost all having the first show symptoms, The higher the temperature patients, the more serious the extent it was twitching, the duration of the disorder of consciousness was longer. |
PDF Full Text Request