| Since China entries into WTO, our pharmaceutical industry has become one of the fastest growing industries, but Chinese pharmaceutical industry's international competitiveness is not improved significantly with scale. Compared with foreign pharmaceutical manufacturing, our technical innovation efficiency still has considerable gap. How to speed up the pace of technical innovation, improve efficiency, and gradually change from the large medical producing country into the technical innovation country based on the rapid development of high-tech, transform economic growth mode of pharmaceutical industry, has become the major subject to be solved.This thesis uses inter-external industry efficiency theory and the latest achievements of method research results for reference, with the character of pharmaceutical manufacturing technical innovation, use nonparametric decomposition framework to test provinces and various sub-industries in pharmaceutical manufacturing about the differences in technical innovation efficiency and the rules that change with time. Based on the evaluation of technical innovation efficiency, this paper uses econometric methods to do empirical study on the main influence factors of pharmaceutical manufacturing technical innovation. According to the existing problems in our pharmaceutical manufacturing technical innovation efficiency based on the empirical research conclusions, this paper provides corresponding solutions.The research results are mainly embodied in the following respects:1. For pharmaceutical manufacturing, new product development is the foundation of their existence and development. Pharmaceutical manufacturing competition is the competition of new drugs. So lowering cost and improving the research efficiency is the trend of pharmaceutical manufacturing development. Through the current situation analysis of pharmaceutical manufacturing technology innovation in USA, Japan and India, this paper finds the experiences of Japan and India that the technology innovation can promote the development of pharmaceutical industry have significant reference for our pharmaceutical industry development. These experiences are as follows:strengthening the government support and intervention, playing the important role of medical college and academy in manufacturing innovation, making enterprises become the subject of innovation, acting according to the international standard production, walking the line of international cooperation and so on.2. According to the characteristics of pharmaceutical manufacturing technology innovation, this paper fixes the innovation efficiency evaluation index system. The static measurement results show that:the technical innovation efficiency of Chinese pharmaceutical manufacturing has regional differences; the eastern and western show relatively effective in technical innovation; the central area is invalid due to the common influence of pure technical efficiency and scale efficiency. The main reason is the R&D activities and the R&D investment funds appear redundant. The dynamic efficiency measurement results show that: Chinese pharmaceutical manufacturing technical innovation efficiency has both regional differences and industry differences. During 1999 to 2007, annual increase of technical innovation efficiency is 6.6%, while technical progress contributes 10.6%.The negative growth of-3.6% in technical efficiency weakens the contribution of technology progress, and finally affects the overall improvement of innovation efficiency.Comprehensive evaluation shows that technical progress is the key point to promote technical innovation efficiency of Chinese pharmaceutical manufacturing, but regional and industry differences in efficiency reflect the importance of reasonable allocation in the process of innovation and the attention degree of independent intellectual property rights in the creative output.3. This paper puts forward basic hypotheses on the influence factors which affect the technical innovation efficiency in pharmaceutical manufacturing from three dimensions:the innovation resources allocation, market structure and system environment, at the same time uses the random effects model to do empirical research on those influence factors.The empirical research shows that:the incensement of R&D investment intensity, rapid growth of the industry, market concentration, opening degree and the incensement of government's investment in science and technology promote the technical innovation efficiency; excessive human capital investment and low assets utilization ratio hinder the enhancement of the technical innovation efficiency; in pharmaceutical enterprises, the proportion of state-owned shares has dual influence on pharmaceutical manufacturing technical innovation efficiency.4. Based on the empirical study results, this paper combines the current situation of the new healthcare system reform to give suggestions. That is to strengthen the management of innovation resources allocation and investment, to accelerate the market structure adjustment and upgrade industrial structure, to improve system environment. Conclusions have reference value for our government to set the pharmaceutical industry policies and guiding significance to enhance pharmaceutical manufacturing technical innovation efficiency.
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