| Objective: Assemble and sort literature on Guizhi-Fuling Pill in successive dynasties so as to reveal its regular application pattern and to induce and extract its contemporary indications and symptoms.Methods: Take thoroughly possession of relevant documents, which could be classified into five types such as prescription, discussion on prescription, pharmacological and empirical study, medical record and clinical observation and draw out information accordingly. Pairing method was adopted to analyze the first three types of documents while statistical method to the others. The experience of using Guizhi-Fuling Pill in ancient times was summed up in three ways, namely spectrum of disease, constitution of patients in point and typical indication. So did the domestic experience, experience in Japan and the individual experience from the clinical practice of Professor Huang Huang respectively.Results: 1. The indications and symptoms of Guizhi-Fuling Pill both in ancient times and up to date were concluded by document statistics and analysis. 2. Considering epoch and academic background, the reasons of coming into being and determinative factors of the indications and symptoms mentioned above were analyzed. 3. Consummate and systematic indications and symptoms of Guizhi-Fuling Pill were induced through contrasting and synthesizing the indications and symptoms in past dynasties. 4. Discussions were made on clinical use of Guizhi-Fuling Pill, for instance, symptom diccrimination, herb gesus, dosage, form and taboo.Conclusions: 1. main spectrum of disease: pathophysiologically, Guzhi-Fulin pill could be primarily used for the following diseases, including diseases in obstetrics, post-operation diseases in gynecology, hyperplasia lump, inflammation in close cavity, circular and vascular disease, endocrine and metabolic disease, abnormal syndrome of autonomic nerve, ophthalmological disease and some certain diseases in dermatology. 2. Constitutions: child-bearing and climacteric period mainly for female, above 60 years old for male. The patients are usually moderate size, have firm and tight muscle, red or dark red face. Rubeosis angiotelectasis or colored spot can be seen on the face. Patients are self conscious of heat sensation, having dark red oral lips; instable emotion and liable of dysphoria and agitated, often in company with headache, vertigo, insomnia, morbid forgetfulness and other symptoms in psychological and nervous system; or having pectoralgia, chest distress, palpitation, sore waist, lumbago, lower abdomen pain and other symptoms of body; asteatosis cutis, scaling, especially on the lower limbs, feeling frosty in the lower limbs. women patients usually have irregular menstruation, algomenorrhea, menstruation delay, amenorrhea or low menstrual blood volume, dark violet menstruation, blood clot; repletion, tense abdominal wall, counteract when palpated, tenderness, especially common in left lower quadrant, dry and hard stool. 3. Typical indications: face indications, abdomen indications and leg indications. Face indications include a series of face, head and psychological and nervous symptoms, such as blush, rubeosis, or dark face, angiotelectasis on the face or wings of nose, coarse facial skin, or alopecie, acne; or accompanied by agitation, dysphoria, insomnia, headache, dizzy, palpitation, contracture in shoulder and neck, thirsty but not wanting to drink and so on. Abdomen indications include self-conscious pain in the lower abdomen, such as vague pain, crymodynia, pricking pain, gas pain, menstruation pain and so on. They also include symptoms that can be observed by doctors, such as counteract, lump, induration, tenderness and etc. According to experience of Japanese doctors, tenderness and counteract appearing on the left have more significance when diagnosing. Leg indications include dark skin on the lower limbs, dry skin, pruritus, desquamation, varication, floating and exposed bluish tendon; liable to leg convulsion, feeling chilly below knees or frostbit and so on. |
PDF Full Text Request