Traditional Chinese Medicine Study On Syndrome Investigation And Clinical Treatment Of Allergic Rhinitis In Singapore

BackgroundAllergic rhinitis is a disease with rhinocnesmus, nasal obstruction, sneezing and turbid nasal discharge as main symptoms, and has sudden onset, recurrent, persistent and refractory characteristics. According to its clinical symptoms, the allergic rhinitis is attributed to the areas of "Bi Qiu " , in the theory of Chinese medicine, which believes that allergic rhinitis is the disease due to the deficiency of lung, spleen and kidney. The internal causes are the deficiency of lung, spleen and kidney inducing weakness of nose and eyes, and the external causes are cold or odor air passing through the lung to induce the disease. For the treatment of allergic rhinitis, Western medicine focuses on alleviating the body's sensitivity to allergens, and can not change radically the physical allergy, anti-allergy and the effect of hormone therapy is also far from obvious. Chinese medicine in the treatment and prevention of allergic rhinitis has a very unique advantages, and mild in nature but should be all good, plus the Singapore Chinese medicine widely used in scientific enrichment, in order to promote Chinese medicine treatment provided a great convenience.Prevalence rate of allergic rhinitis in Singapore is high and has an increasing tendency, in which the cases with deficiency of Lung and cold syndrome are most common. This is closely related to the environmental factors of Singapore and the region. Singapore is an area in summer all the year round. The high temperature in summer release and open on human's skin and fur, which is susceptible of exogenous evil. Due to the high usage of air conditioning in Singapore, it is summer outdoor and "late autumn" in the room. When people are in and out of air-condition rooms, alternating hot and cold air, it is easy to cause invasion of exogenous evil. Since Singapore is a four-season summer area, people consume more energy and experience faster metabolism. Therefore, the crowd physique in Singapore is generally thin and weaken in Qi. In addition, the people in Singapore usually have daily meals outside most of time. This makes them have more fat, sugar and salt intake than normal. Due to heat and wetting weather, the people also like spicy food and cold drinks. Therefore, Singapore's geographical location, population health and eating habits make the people in the region with the characteristics of lung weak and vulnerable, and being sense of cold-induced allergic rhinitis.PurposeIn this paper, the clinical study has two parts: (1) syndrome investigation and (2) clinical treatment. The aim of the syndrome investigation is to determine the major clinical syndrome type and other characteristics of the allergic rhinitis in the area of Singapore; and the aim ofthe clinical study is to analyses different treatment methods for lung-cold allergic rhinitis.MethodsSyndrome investigation A total of 250 cases of allergic rhinitis symptoms have been collected,and the investigations have been made from 5 aspects, including syndrome type, age and sexcomparison, complications, distribution of illness-condition and course of disease etc.Clinical treatment Choosing 91 patients with lung-cold allergic rhinitis which are divided into 3 groups: group A (medicine and acupuncture group) - 35 patients, treated with combining traditional Chinese medicine and acupuncture; group B (medicine group) - 32 patients, treated with traditional Chinese medicine; group C (control group) - 24 patients, treated with oral tablets. The clinical data are analyzed with medical statistical methods, including average, standard deviation, percentage, independent samples t test and so on, to carry out statistical analysis of the effect.Results(A) Syndrome investigation1. In the investigation, it is found that the patients with the lung-cold type allergic rhinitis are majority, accounting for 64.8%; followed by the spleen-weak type allergic rhinitis, accounting for 23.2%. Therefore, the lung-cold allergic rhinitis is selected as the object of study and treatment.2. The patients younger than 19-year-old are the largest proportion, reaching 50.4%. With the increase of age, the proportion of the patients with the allergic rhinitis is reduced. The ratio of the male and female sex patients is 1.1:1.3. The majority of the patients with allergic rhinitis have no complications, reaching 71.1 %. In the cases of the allergic rhinitis patients with complications, more patients are allergic rhinitis with asthma. The cases of the allergic rhinitis with eczema and the allergic rhinitis with asthma and eczema are very few.4. The patients' illness conditions and courses have similar distributions. The patients with medium illness-condition are in the highest proportion, reaching 34.4%, and the patients with light or serious disease are in lower ratio. The patients with 1-5 years of the disease are in the highest proportion, accounting for 40.0%; and the patients with the disease more than 5 years or lower than one year are in lower ratio.5. Most patients with allergic rhinitis have a family history, accounting for 73.2%. (B) Clinical treatment1. The total treatment rate of the group A is 94.3% (effective rate 68.6%), the total treatment rate of the group B is 81.3 % (effective rate 34.4%), and the total treatment rate of the group C is 50.0% (effective rate 8.3%). Ridit statistical analysis showed that the effect has a significant difference. As a result, the comprehensive treatment effect of the groups A and B is far higher than group C, and the treatment effect of the group A is slightly higher than that of the group B.2. The statisticalμtest results for the total clinical symptoms score differences before and after the treatments show that: (i) the statistical results for group A and group C and for group B and group C all statistically show significant difference. Therefore, the treatment efficacies of the groups A and B are significantly higher than that of the group C. (ii) the statistical results for group A and group B also show statistical difference. Therefore, the treatment efficacy of the groups A is higher than that of the group B.3. The statisticalμtest results for individual clinical symptom score differences before and after the treatments show that: (i) for any individual clinical symptom, the statistical results for group A and group C and for group B and group C all show significant difference. Therefore, the treatment efficacies of the groups A and B are significantly higher than that of the group C. (ii) the statistical results for group A and group B show that for the symptoms of nasal itching, sneezing and runny nose, the treatment efficacy of the groups A is higher than that of the group B, and for the symptoms of stuffy nose, swollen turbinate, the treatment effect of the groups A and B is same.4. The shorter the course of disease is, the better the treatment effect is and the lighter the illness condition is, the better the treatment effect is. And the relevance between the treatment effects and the age and gender are not significant.