The Clinical Study Of Using Tremor Three Needles In The Treatment Of Parkinson's Disease

Background:Parkinson's disease(PD) is a neurological condition that is commonly seen in the elderly,characterized by motor impairment,slowing of physical movement,muscle rigidity,and tremor at rest.The disease is named after the English physician James Parkinson,who made a detailed description of the disease in his essay published in 1817.The prevalence of the disease differs throughout the world.It is most prevalent in Europe and the America,estimated at a rate of 66-187 in 100,000,and Japan at a rate of 37-80.6 in 100,000.The standardized rate in China is 10.8 in 100,000, while that of the world is 15.0 in 100.000.Our rate is far less than the world standard.PD rarely occurs at an age below 40 years old,and the occurrence rate in male is much higher than in female.At present,there is no cure for PD,researches to discover novel drug to treat PD has put into focus.It is a progressive disorder,which makes early diagnosis difficult.Moreover,many diagnostic measures,such as scans, have yet been standardized.Medications for PD can only provide relief from the symptoms.Currently.levodopa(L-dopa) is the most widely used form of treatment.It is transformed into dopamine in the dopaminergic neurons by L-aromatic amino acid decarboxylase.However,long-term use(2-5 years) of L-dopa may induce numerous side-effects,such as nausea,vomiting,anorexia, low blood pressure,the "end of dose" effect,the "on-off" effect. kinematic impairment,and cognitive and behavioral symptoms.Medication is ineffective in approximately 15%of the patients,and the daily dosage would only worsen the symptoms.In hope to minimize the side effect of oral medication,acupuncture as a complementary treatment has become more recognized for its effectiveness and minimal side-effect.However,limited number of researches has been done to prove its effect in the treatment of PD.Objective:To investigate the curative effect of using tremor three needles in the treatment of Parkinson's Disease.Method:A total of sixty PD patients were randomly divided into treatment and control groups,each having 30 patients.The treatment group used acupuncture,mainly tremor three needles,and the control group used mainstream medication(L-dopa).Their clinical symptoms,physical activity, quality of life were observed and recorded before and after treatment.Results:1.After treatment,all indeces in the treatment group significantly improved, except for facial expression,swallowing ability and speech,as compared to the control group.The facial expression in both groups improved,but the change in difference between the groups was not significant.As for swallowing and speech,both groups did not improve after treatment.2.The quality of life significantly improved in the treatment group,as opposed to the control group.After treatment,the treatment group consisted of the following:1 patient clinically recovered,16 extreme improvements,5 moderate improvements,4 slight improvements,5 ineffective:the total effective rate was 83.87%.The control group consisted of 0 patient clinically recovered,9 extreme improvement.6 moderate improvement,7 slight improvement,9 ineffective:the total effective rate was 70.96%.After Ridit anaiysis,Z=2.03,P=0.03(p＜0.05), the change in improvement between the two groups was significant,thus, the treatment group was more effective in the treatment of PD than the control group.Conclusions:The use of tremor three needles in the treatment of PD is effective and can improve the patients' symptoms and quality of life.