Ginseng, Hawthorn Drink The Treatment Of Acute Myocardial Infarction In 62 Cases Of Clinical Observation Summary And Ginseng, Hawthorn Drink On Acute Myocardial Ischemia - Reperfusion Injury Model Effects Of Experimental Study

Objective: To observe the applied clinical efficacy of the Chinese medicine Ginseng Hawthorn Decoction with Western medicine in the treatment of acute myocardial infarction, and observe the experimentation efficacy of Ginseng Hawthorn Decoction no the Wistar rat, that are used as acu(?)e (?)ocardial lack blood-resume the blood infuses Model.Method: (1)The selection clinical case of using Ginseng Hawthorn Decoction with Western medicine in acute myocardial infarction, that all come from the emergency sickroom of the Chengdu University hospital of TCM, the time is from 2000.1 to 2005.12, and The select cases all are 62 patients (The Group of the Chinese medicine with Western medicine in the treatment ); And contrast its corresponding period curative efficiency with the western medicine cases 60 patients in this hospital (The group of the western medicine treatment). The contrasting matters include the obvious curative efficiency, the total curative efficiency, and the die of illness a rate.(2)The rats are used for the animal model of acute myocardial lack blood-resume the blood infuses on the experiment.32 rats are divided into 4 groups randomly, the group of false surgical operation, the group of model, the group of Western medicine treatment (Carvedilol), the group of Chinese traditional medicine treatment (Ginseng Hawthorn Decoction). Then examines the level of the blood NO, MDA, Ang â…¡, ET in the acute myocardial lack blood-resume the blood infuses model 360 minute later. Result: The clinical observation result show that the obvious curative efficiency, the total curative efficiency, and the die of illness a rate is 69.35%, 95.16%, 3.23% in the group of the Chinese medicine with Western medicine in the treatment. It is better than the group of the western medicine in the treatment (58.33%, 80%, 11.67%,P <0.05).The test result show that the Ginseng Hawthorn Decoction and Carvedilol all can heighten the NO level, and lower the MDA, Ang â…¡, ET level in acute myocardial lack blood-resume the blood infuses 360 minute later. But the Ginseng Hawthorn Decoction is better than Carvedilol (P<0.05,0.01).Conclusion: The Group of the Chinese medicine with Western medicine can heighten the clinical curative efficiency, and lower the die of illness a rate in the treatment of acute myocardial infarction; Ginseng Hawthorn Decoction can protect vas endothelium cell, and allay lipid peroxide on the basis of oxygen radicals. Its show that Ginseng Hawthorn Decoction has the protection effect in trauma of acute myocardial lack blood-resume the blood infuses.