The Cardioversion Baoxin Level Oral Solution Ami Rats, Promote Myocardial Angiogenesis And Vegf And Its Mrna Expression

Acute myocardium infarction(AMI) is a very serious diease. Because of coronary occlusion and break off bloodstream, part of myocardium necrosis for endurance lack of blood .Along with improving of living level,AMI is the one of importment died reasons. Systematic studies on the prevention and treatment for AMI by FuLuBaoXinPing oral liquid (FLBXP oral liquid) had been performed from the aspects of reference reviews and experimental study in this essay. FLBXP oral liquid set up its rule on removing stagnation, easing pain and removing obstruction toit, tonifying the kidney and supporting YIN. My tutor advanced a new treat rule of AMI, it is " rely mainly on jab while adjust liver and kidney to cure heart" .The myocardium VEGF through the herb was used in the experimental study of AMI has seldom been reported before . So this assay is practical and innovative .1 Reference reviewThis essay reviewed from the advances of such fields as followed: the etiology and pathogenesis for AMI, selection of treatment or by different stage based on the differential syndrome diagnosis, the treatment of the single herb or its abstract, which is in ancient and modern time, moreover, included the evaluations and prospects on the criterions of diagnosis and curative effect as well as the problems lying in the selection of treatment based on the differential syndrome diagnosis or scientific study. This essay summarized the experimental study results and advances on the principle of preventing and treating AMI, according to the pathogenesis of AMI, such as inflammation, virus, lipoprotein, IL-6, RAS , CRP and so on . It also included evaluations and prospects on these above. The research trends of promoting the lateral branch circulation of coronary artery were summarized involving the pathogenesis of AMI recant years.2 theory StudyBy discussing the headstream, name gist, Chinese diagnosis, differentiation of symptom-complex, the important point of diagnosis and treat, principle and method of treat etc. of Xiong bi xin jue with Chinese medicine theories quoting from classics works and combining modern research result. We also put forward the main treat rule which is the valid way to cure it.3 Experimental study3.1 The influence about FLBXP oral liquid to ET NO and myocardium infarction areain experimental of acute myocardium infarction ratsAMI rats were divided randomly into high dosage of FLBXP oral liquid group, low dosageof FLBXP oral liquid group, postive control group, AMI model group, pretend operationgroup. The results showed high dosage of FLBXP oral liquid obviously reduce the rats'ET concent , which had a significant statistic sense in comparing with AMI modelgroup ( RO. 01). And high dosage of FLBXP oral liquid obviously improve the rats'NO concent , which had a significant statistic sense in comparing with AMI modelgroup ( RO. 01). High dosage of FLBXP oral liquid also obviously reduce the rats'myocardium infarction area , which had a significant statistic sense in comparingwith AMI model group ( RO. 01). The function that FLBXP oral liquid reduce the rats'myocardium infarction area maybe relate to improving NO and reducing ET and modifyingthe endocrine function of endothelium cell.It is pointed out that the function which FLBXP oral liquid reduce the rats'myocardium infarction area maybe relate to improving NO and reducing ET and modifyingthe endocrine function of endothelium cell.3. 2 The research about FLBXP oral liquid to resist fat peroxidation in experimentalAMI ratsAMI rats were divided randomly into high dosage of FLBXP oral liquid group, low dosageof FLBXP oral liquid group, postive control group, AMI model group, pretend operationgroup. The results showed high dosage of FLBXP oral liquid obviously improve therats' SOD concent , which had a significant statistic sense in comparing with AMImodel group ( RO. 01). And high dosage of FLBXP oral liquid obviously reduce therats' MDA concent , which had a significant statistic sense in comparing with AMImodel group ( RO. 01).It is pointed out that FLBXP oral liquid has obv...