Chronic Atrophic Gastritis Nearly 10 Years Of Chinese Literature

This study with the database, data mining, and other means, for nearly 10-year domestic public Chinese medicine or or integrated traditional Chinese and Western medicine in treatment of chronic atrophic gastritis in the literature as the research object, using frequency analysis, factor analysis, principal component analysis, cluster analysis, as well as associatedrules, data mining methods, respectively syndrome factor on the CAG, syndromes, different aspects of drug law and related analysis and processing, to summarize the treatment of CAG experience, to do an experiment and explore; for the combination of theory and clinicalprovide a platform;Objective:Using data mining method on CAG syndrome, syndrome factor, pathogenesis and drug law from different perspective;to improve the CAG syndrome differentiation system makes beneficial exploration, for clinical in prescriptions with mode of thinking and decision-making basis.Method:1.Retrieval 2000-2011 China Academic Journal (CNKI) and related databases, the relevant literature;2.Data preprocessing:check against Syndrome type name, symptoms name, name of the drug to be regulated;3.Establishment of a database:the original database input excel database through computer programming;4.Use of frequency analysis, factor analysis, principal component analysis, cluster analysis, frequent itemsets, association rules data mining methods for data mining.(1)Use of frequency analysis for Syndrome, syndrome elements, targeted to carry out frequency analysis.(2)Use of frequency analysis, frequency analysis, factor analysis, principal component analysis, cluster analysis for symptom data mining.(3)Using frequency analysis, factor analysis, principal component analysis, cluster analysis, data mining on Chinese herbal medicine.(4)Use of frequent itemsets and association rules data mining on Chinese herbal medicine and Chinese herbal medicine, symptoms, and Chinese herbal medicine.Result:1.Use of mathematical statistics on the study of Chinese literature in the past decade, and found:CAG differentiation of type, reference standards are not uniform,CAG syndromes, symptoms, Chinese herbal medicine names are not standardized, which restricts the CAG clinical applications and exchange of technology2.Using the method of mathematical statistics on CAG nearly ten years literature of traditional Chinese medicine extract its main syndrome elements, targets and their combination rule; TCM syndrome has changed a lot, and syndrome factor, target relative simplicity, multivariate statistical method can better reveal the complex combinatorial relation;3.Symptom cluster analysis of CAG syndromes grouped into nine categories, namely:spleen-stomach weakness syndrome,stomach yin deficiency syndrome, syndrome of liver qi invading the stomach, syndrome of depressed liver and stomach qi transforming into fire, syndrome of dampness-heat in the spleen and stomach, syndrome of liver depression and qi stagnation, syndrome of (blood) stasis in the stomach collateral, spleen yang deficiency syndrome, stomach heat syndrome, etc.4The drug frequency analysis, found the tonic medicinal, regulating qi medicinal, heat-clearing medicinal use with high frequency, which tonify qi medicinal of CAG is nonspecific drug;5.Based on the cluster analysis of CAG Chinese herbal medicine, formed 7 kinds of clustering method, from the functional perspective, including:reinforce the healthy qi, eliminate the pathogenic fanctors, reinforce the healthy qi and eliminate the pathogenic fanctors.6.Drugs and drug association analysis and found that Decoction of Sijunzi Decoction of Er chen, moving qi and activing blood medicinal is the medicine treatment CAG basic recipe, between the three applications constitute the general laws of the physician medication.7.Associated symptoms with herbs and found that the core symptoms:torpid intake, belching, epigastric pain, epigastric fullness, the core of herbs:Zhigancao, Poria, Atractylodes, Codonopsis, Astragalus, dried tangerine peel. Therefore infer that the the CAG syndrome elements is qi deficiency and qi stagnation, target is liver and spleen; basic syndrome type of CAG is liver stagnation and spleen deficiency.Innovation of this study:1.Rational use of" syndrome factor" and the" target" and" evidence combination rule " ideas, combined with data mining methods to CAG nearly 10 years periodical literature systematically, and propose own point of view on the diagnosis and treatment of CAG.2.The CAG syndromes, syndrome factor, pathogenesis, drug law were summarized from the literature point of view, using data mining from the literature point to explore the CAG syndrome characteristics and herb law.