Clinical Research Of "Connecting And Regulating Ren Du Acupuncture" For Primary Insomnia

Objective:To explore the curative effect and review each particular advantage of "connecting and regulating Ren Du" acupuncture and conventional acupuncture for primary insomnia, by observing and comparing the change of Pittsburgh sleep quality Index (PSQI) and TCM symptoms accumulate points,moreover, by observing the influence to sufferers'brain function of these two acupuncture therapy, thus,to provide initial investigation of "connecting and regulating Ren Du" basis theory, and offer a new train of thought and a new therapy of acupuncture for primary insomnia.Methods:1,120primary insomnia cases that met including criteria randomized controlled,were divided into2groups:"connecting and regulating Ren Du"acupuncture group(treatment group) and conventional acupuncture group (control group), including3types of syndromes:44cases heart-kidney imbalance,44cases liver-spleen imbalance, and32cases heart-spleen deficiency.2,In the treatment group,4points of Ren Meridian(RM) and Du Meridian(DM) were be used,to active yang and strengthen the body resistance.In control group points of tranquilization and calm the nerves function were be used, the two groups all compounded with shu-back points,and points-yuan etc.To give treatment every other day, each time remaining needles30minutes.The treatment process is4weeks, then to assess curative effect after each week;and to follow-up visit after1month and3month.3,To compare curative effect intergroup and each type of syndrome,to observe the change of sleeping factors,clinical TCM symptom pretherapy and post-treatment, by assessing Pittsburgh sleep quality Index (PSQI),TCM symptoms accumulate points and Epworth sleepiness scale.4,To discuss the effect of these two acupuncture therapy for sufferers'brain function, by observing and comparing results of awake electroencephalogram(EEG) and event-related potential(ERP)P3check.Results:1.The curative effect comparison:After treatment, the effective rate and cure rate of two groups are different (P<0.025,P<0.05). Treatment group exceed control group in effective rate and cure rate.In Treatment group,there are27.1%patients gain effect within1week, and70%patients gain effect after2weeks;In control group, there are6.9%patients gain effect within1week, and29.3%patients gain effect after2weeks(P<0.01). For each syndrome the cure rate between the groups is differente, that treatment group exceeded control group(P<0.05). Moreover,for heart-kidney imbalance syndrome, treatment group is exceeded control group in both the cure rate and effective rate(P<0.05).2.The change of scale score:After treatment scores of PSQI,Epworth,and TCM symptom accumulate points have both decreased(P<0.01).Deductions of treatment group is lower than control group(P<0.01).For treatment group,the deduction of sleeping factors and TCM symptom points all have decreased(P<0.01),yet, for control group only part of them have decreased.3.Brain function assaying:Comparing pretherapy, there are no changes among two groups and each type syndrome for the results of awake EEG test and ERP check(P>0.5), and the delitescence of P3has be shortened in two groups (P<0.01, P<0.05),furthermore, the change in treatment group is even evidently(P<0.01).However, there are no difference in the change of amplitudes for two groups after treatment(P>0.05)Conclusion:1.The curative effect of "connecting and regulating Ren Du" acupuncture therapy is good than conventional acupuncture therapy. The ascendency is be showed even evidently for heart-kidney imbalance syndrome.The short term and,far term curative effect for insomnia of "connecting and regulating Ren Du"acupuncture therapy is steady,which is worth popularizing in clinic.2.Comparing control group,"connecting and regulating Ren Du" acupuncture therapy is even more completely ameliorate patients'clinical symptom,and is more excellent at ameliorating difficulty of fall sleep,early awakening, shortening hours of sleep,and removing residual effect in the next day, such as sleepiness and exhaustion,dizzy or headache,forgettery, agitation and irritation emotions.3.It's not sure that these two acupuncture therapies can change the awake EEG test and ERP check results, but they all can ameliorate the state of brain function,"connecting and regulating Ren Du" acupuncture therapy's effect is better than conventionality acupuncture therapy's.