| A cross-sectional study was designed to investigate the relationship between hypertension and serum lipids and apolipoproteins, insulin and polymorphism of the ACE gene. Migration from rural to urban in the province provided an ideal opportunity to examine the effects of genetic and environmental factors on blood pressure. Results of this study provided valuable clues to the prevention and control measures of hypertension.Epidemiological methods as well as biochemical and molecular-biological techniques were used. The study fields were located on Xichang city, Puge County and Zhaojue County in Liangshan Yi People Autonomous Prefecture, Sichuan Province. Three groups of populations aged 15 years or more were selected by cluster sampling, including 1113 aboriginal Yi farmers, 1034 Yi migrants and 1039 Han residents. Yi farmers have been living in a high — mountainous areas at about 2000-3000 meters above sea level. Isolated from the outside world, Yi farmers have preserved their own language and primitive life-style. The principal components of their diet are potatoes, buckwheat and oats. Meat is seldom consumed, only limited to weddings, funerals, and biannual celebrations( the Torch Festival in July and the Yi new year in November). Animal fat and vegetable oil are rarely used for daily cooking. Yi migrants in this study were born in the high mountainous areas and migrated to the counties or to Xichang 5 years or more prior to the survey. Yi migrants and Han residents have the same dietary staples: rice, meat, fresh vegetables and fruits.From October to December of 1996, the survey was conducted. Questionnaire comprising age, race, years of migration, current smoking and alcohol drinking habits, physical activity and familial and individual history of hypertension were administered by local health workers who were fluent in the Yi and Han languages. Height, weight, circumferences of the waist and hip, and blood pressure were measured. About 200...
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