Clinical Investigate Of Intracoronary Ultrasound And Self-expanding Stent-Radius

Part 1 Comparison of Angiography, Quantitative Coronary Angiography and Intracoronary UltrasoundObject: Previous studies have demonstrated that angiography, even QCA can not provide accurate coronary artery disease morphology, there is no systematic comparison of disease morphology determined by angiography, QCA and ICUS. The purpose of this study is to compare the outcome of Angiography, Quantitative coronary angiography (QCA) and Intracoronary Ultrasound (ICUS) for coronary artery disease.Methods: 156 patients with coronary artery disease were studied. A total of 185 coronary stenosis site which underwent interventions were enrolled. The percent stenosis, eccentricity index (El) and lesion length were determined. The El was calculated by the formula: {(max-min) / max} x 100.Results: The minimal lumen, severity of the stenosis and El determined by ICUS are 1.2±0.3mm, 74.4±11.5% and 0.58±0.41, which did not differ from that by QCA (1.0±0.5mm,68.4±17.5% and 0.48±0.31, p>0.05 respectively). There was no correlation between them. Lesion length determined by QCA (18.6±7.8mm) was significantly shorter than that by IVUS (24.6±5.8 mm, p<0.01). The number of calcified lesion detected by ICUS was larger than by QCA (67 vs. 36, p<0.01). The percent stenosis and lesion length determined by angiography is significantly differ from that by ICUS and QCA.Conclusion: These results demonstrate that coronary angiography and QCA significantly misinterprets disease morphology in terms of stenosis severity, eccentricity, length and calcification. ICUS is accurate in determining morphology of coronary artery disease . It is a good method to combine QCA with ICUS for studying the restnosis after PTCA.