Clinical Effect Of Qilongdingchuan Plaster On Cough Variant Asthma With Spieen And Kidney Deficiency

Objective : To observe the clinical effect of Qilong Dingchuan Ointment,a traditional Chinese medicine ointment,combined with budesonide and fumoterol powder inhalation in the treatment of patients with cough variant asthma of spleen and kidney deficiency type.To compare the daily variation rate of peak expiratory flow rate(PEF),exhaled nitric oxide(Fe NO),cough visual analogue score(VAS),Laisaist cough quality of life questionnaire(LCQ),traditional Chinese medicine syndrome score The effective rate and recurrence rate after treatment provide evidence-based basis for improving the efficacy of traditional Chinese medicine in treating cough variant asthma.Method : The study observed and collected 86 patients who met the inclusion criteria from the respiratory inpatient and outpatient departments of Qinhuangdao Traditional Chinese Medicine Hospital from October 2020 to October 2022.According to the random number table method,they were divided into two groups,with 43 cases in the control group and 43 cases in the experimental group.The control group was treated with inhalation of budesonide and formoterol powder.The experimental group was treated with Qilong Dingchuan ointment on the basis of the control group.Compare the daily variation rate of peak expiratory flow rate(PEF),exhaled nitric oxide(Fe NO),cough visual analogue score(VAS),Lesser Cough Quality of Life Questionnaire(LCQ),and traditional Chinese medicine syndrome score between two groups before and after treatment.Compare the main symptoms(cough),secondary symptoms(edema,soreness of the waist and knees,fear of cold limbs,loose stools),and treatment effectiveness of cough variant asthma between the two groups before and after treatment.Follow up after 4 weeks,Monitor the patient’s recurrence status.Simultaneously record the patients who fell off and any adverse reactions that occurred.Use statistical software SPSS27.0(Chinese version)for data analysis and processing.Result : 1.Before treatment,baseline data of both groups of patients,including gender,age,and course of disease,were obtained.During the experimental observation,3 out of 86 patients experienced detachment Before treatment,the two groups were compared in terms of gender,age,course of disease,daily variation rate of peak expiratory flow rate(PEF),exhaled nitric oxide(Fe NO),cough visual analogue score(VAS),Lesser Cough Quality of Life Questionnaire score(LCQ),traditional Chinese medicine syndrome score,etc.,with no statistical significance(P>0.05)and comparability The VAS score,LCQ score,Fe NO value,and PEF value of the two groups of patients were significantly different before and after treatment(P<0.01).The difference between the experimental group and the control group after treatment was statistically significant(P<0.05)There was a statistically significant difference(P<0.01)in the main symptom score(cough)and secondary symptom score(edema,soreness and weakness of the waist and knees,fear of cold limbs,and loose stools)between the two groups of patients before and after treatment.The difference between the experimental group and the control group after treatment was statistically significant(P<0.05)The clinical efficacy rate was 95.12% in the experimental group and 71.42% in the control group,with a statistically significant difference(P<0.05)The recurrence rate was5.1% in the experimental group and 33.3% in the control group,with a statistically significant difference(P<0.05).(6)Safety analysis: Both groups of patients showed no significant abnormalities in body temperature,respiration,blood pressure,cardiac routine(blood,urine,stool),liver and kidney function,and 12 lead electrocardiogram before and after treatment,indicating that both treatment plans had good safety.Conclusion : Qilong Dingchuan Cream can effectively increase the daily variation rate of peak expiratory flow velocity in patients with cough variant asthma of spleen kidney deficiency type,improve inflammation levels and cough symptoms,and alleviate patient pain;The treatment process has good safety,no adverse reactions,and a definite therapeutic effect,which is worthy of clinical promotion.