| Impartial:To investigate its therapeutic potential of reconfigured Maxing Shenling Baizhu granules in managing allergic bronchopulmonary health care workers with bronchi and kidney and liver shortage and continuing to improve pulmonary inflammatory processes from the moment of that first increased incidence,and also to objectively measure its efficacy and security,in order to offer novel approaches and fresh suggestions for the diagnosis of airway inflammation with traditional Chinese medicine,and to enhance the clinical management capacity of individuals with bronchiec.Mechanisms:A combination of 60 adolescents were involved in the trial,with 57 completing it,29 in the intervention group and 28 in the comparison group.The placebo group got pro government,difficulty in breathing,and other clinically standard care.On the basic principle of the comparison group’s medication regimen,the research group was provided with Maxing Shenling Baizhu Powdered.The treatment sessions monitoring duration was 4 months,of which the treatment period was 1 month and the obey duration was 3 months.The date from the start of taking medication to the first exacerbations of each client was logged during the duration of the study,and a clinical effectiveness assessment was performed on the complaints of traditional Chinese medicine,bronchial fluid generation,intracellular immunological performance,and incendiary level preceding and following therapy and adopt,as well as the hazard appraisal of the kidneys and liver mechanism.Results:1.Descriptive characteristics: there was not a quantitatively noteworthy distinction among the two subgroups’ basic information preceding surgery.In regard to sexual orientation,women outnumbered males in both categories.The average life expectancy of the two different groups is around 62 years old,with the bulk of persons between the ages of 50 and 75.The cumulative number of individuals who smoked in the two categories was 23,with 47.8% of the cigarettes from 10 to 30 years old.The greatest illness history is 41 years,while the lightest is 6 months.The most individuals are found between 10 and 30 years following admission,representing for56.1% of the total.The BSI scores of the two groups were comparable Private citizens with much more than nine points made up 65.5% of the experimental and control groups and 53.6% of the control group.2.Time to first relapse: 7 patients(23.3%)in the experimental class and 5patients(16.7%)in the control condition were devoid of asthma exacerbation during the 4-month therapy and obey.The interventional group’s average amount of time to severe recurrence was 93.3 days,8.5 weeks longer than the control company’s.The proportional hazard Cox r-squared,on the other hand,revealed that the mathematical distinction between the two distinct groups was not meaningful.3.Mucus secretion in the respiratory tract: This study examines pre-and post-treatment scores as well as intra-group ratings.When comparing the area of cough symptoms before and after treatment,there is no statistically significant difference between the two groups;the comparison between the groups revealed that the scores were higher in both groups than before treatment,with a statistically significant difference,indicating similar effectiveness in controlling cough symptoms.There were statistically significant changes between groups after treatment for regions affected by cough,expectoration symptoms,and areas impacted by expectoration and before to treatment.4.TCM syndrome efficacy and score comparison: Following treatment,the experimental group’s overall effective rate was higher than the control group’s,at96.6%(28/29)and 82.1%(23/28),respectively.After therapy,there were significant variations in the overall scores of TCM syndrome between the two groups.Cough,sputum volume,sputum quality,chest tightness,shortness of breath,weariness,little food and stomach distension,tasteless mouth,loose stools,pale skin,and other TCM symptoms were shown to be significantly different(P < 0.05,P < 0.001).5.Cellular immune function: After treatment,there was a significant difference in the experimental groups,with a rise in the proportion of CD4+,CD4+/CD8+ cells and a decrease in the proportion of CD8+ cells.Only after therapy did the fraction of CD4+ cells in the control group increase statistically.In contrast,there was a statistically significant difference between the CD8+ and CD4+/CD8+ ratios,but no statistically significant difference between the two CD4+ groups.6.All inflammatory markers were compared between the two groups before and after therapy,including WBC,NEUT%,and CRP.The effectiveness of both groups in reducing WBC was minimal and comparable.The CRP’s efficacy was not noticeably different.Intragroup comparisons revealed a statistically significant difference in the experimental group’s NEUT% control rate before and after treatment,but not in the control group.7.Safety indicators: There were no statistically significant differences between indicators of liver and kidney function before and after treatment.Safety effects were observed during treatment.Conclusion:1.Clinical routine treatment plus taking Maxingshenlingbaizhu powder can delay the time of acute exacerbation to a certain extent;2.Maxing shenling Baizhu Powder can improve airway mucus hypersecretion and relieve airway obstruction symptoms in patients with lungqi deficiency type branch enlargement;3.Depending on the clinical characteristics of patients with deficient cardiopulmonary branches,in addition to conventional treatment,albatrose ginseng with ginseng is effective in improving various clinical symptoms,improving immune function and,to some extent,controlling the progression of chronic inflammation.4.In this study,no adverse reactions were found,indicating that the addition and reduction of Maxing Shenling Baizhu Powder has good safety performance in the treatment of lung qi deficiency type branch enlargement,and has application and popularization value. |
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