| Objective:By observing the clinical efficacy of Shenling Baizhu powder combined with metformin in the treatment of overweight/obese type 2 diabetes patients with spleen deficiency and dampness and drowsiness syndrome,to explore and analyze the clinical efficacy and mechanism of Shenling Baizhu powder combined with metformin,so as to provide clinical treatment for overweight/obese type 2 diabetes mellitus.Provide ideas.Methods:From July 2021 to December 2021,80 overweight/obese patients with type 2 diabetes who met the diagnostic criteria in the Department of Endocrinology,Department of Traditional Chinese Medicine,and outpatient departments of Wuhan Integrated Traditional Chinese and Western Medicine Hospital were selected as the research objects,and they were randomly divided into two groups.Observation group and control group,40 cases in each group.The two groups were arranged with diabetes and obesity-related health knowledge education,scientific diet,and appropriate physical exercise.The control group was given metformin tablets（0.5g/time,orally half an hour before breakfast and dinner）,and the observation group was given ginseng supplementation on the basis of the control group.Lingbaizhu Powder（15g of ginseng,15g of Atractylodes,12g of Poria,15g of Chinese yam,15g of white lentils,9g of Coix seed,9g of lotus seed flesh,6g of Amomum,6g of Platycodon grandiflorum,10g of licorice,decocted in water,1 dose per day,divided into two times service）treatment.2 weeks as a course of treatment,a total of 4 courses of treatment were observed.The blood glucose（FPG,2hPG,HbAlc）,blood lipids（TC,TG,LDL）,obesity（BMI,WHR,obesity degree）related indicators and TCM syndrome scores before and after treatment in the two groups were observed and evaluated.Results:1.All the data in this experiment conformed to the normal distribution,and there was no significant difference in the distribution of gender,age and disease duration between the two groups（P>0.05）.2.There was no significant difference in blood glucose indexes（FPG,2hPG,HbAlc）between the two groups before and after treatment,and the difference was not statistically significant（P>0.05）.The blood glucose indexes in the two groups after treatment were lower than those before treatment,and the difference was statistically significant（P<0.05）.After treatment,the blood glucose indexes in the observation group were lower than those in the control group,and the difference was statistically significant（P<0.05）.3.The comparison of blood lipid indexes（TC,TG,LDL）between the two groups before treatment showed no statistical significance（P>0.05）.After treatment,the blood lipid indexes in both groups were lower than those before treatment,and the difference was statistically significant（P<0.05）.The comparison of blood lipid indexes between the two groups after treatment showed that the observation group was significantly lower than the control group,and the difference was statistically significant（P<0.05）.4.There was no statistical significance in the comparison of obesity indicators（BMI,WHR,obesity degree）between the two groups before treatment（P>0.05）.The obesity indexes in both groups after treatment were lower than those before treatment,and the difference was statistically significant（P<0.05）.After treatment,the obesity index between the two groups was compared,and the observation group was significantly lower than the control group,and the difference was statistically significant（P<0.05）.5.The comparison results of TCM syndrome scores between the two groups before treatment showed no comparability（P>0.05）.After treatment,the TCM syndrome scores in both groups were lower than those before treatment,and the difference was statistically significant（P<0.05）.After treatment,the TCM syndrome scores between the two groups were compared,and the observation group was significantly lower than the control group,and the difference was statistically significant（P<0.05）.6.The comparison of the efficacy of traditional Chinese medicine showed that the total effective rate of the observation group was 90%,the total effective rate of the control group was 75%.And test,the two groups of curative effect comparison was statistically significant（Z=3.056,P=0.002<0.05）.Western medicine efficacy comparison showed that the total effective rate of the observation group was 87.5%,the total effective rate of the control group was 75.0%.And test,the two groups of curative effect comparison was statistically significant（Z=3.139,P=0.002<0.05）.Conclusion:On the basis of diet control and reasonable exercise treatment,metformin combined with Shenling Baizhu Powder can effectively reduce the levels of blood sugar and blood lipids in overweight/obese patients with type 2 diabetes mellitus,improve the metabolic status of glucose and lipids,reduce the degree of obesity,and can improve the clinical symptoms of traditional Chinese medicine.There are also positive effects. |
PDF Full Text Request