The Clinical Study Of On The Treatment Of Chronic Pelvic Floor Pain Syndrome(Qi-stagnation And Blood-stasis Type) With Juhe Wan Plus Or Minus

Objective:To excavate,summarize,analyze and sum up the academic thoughts and clinical experience in the TCM treatment of male chronic pelvic floor pain syndrome-qi stagnation and blood stasis type,and objectively evaluate the efficacy and safety of"Juhe Wan plus or minus"in the treatment of chronic pelvic floor pain syndrome of qi stagnation and blood stasis type.Methods:The randomized controlled study method was adopted.Seventy-two patients who met the inclusion criteria from the andrology clinic of the Affiliated Hospital of Changchun University of Traditional Chinese Medicine were included in the treatment observation subjects.The final total sample size was set as 72 cases,36 cases in the treatment group and 36 cases in the control group,They were randomly divided into treatment group and control group.The overall improvement rate of disease efficacy was used as the main efficacy evaluation index in the trial.The aim of this study was to compare“Juhe Wan plus or minus”with“Xuefu Zhuyu Jiaonang”.According to the general principle of treating male chronic pelvic floor pain syndrome from qi stagnation and blood stasis,the treatment was to regulate qi and relieve pain,promote blood circulation and remove blood stasis.The subjects were orally treated for 28 days.Observe before treatment and after treatment,that is,before treatment(-7d～0d),after the end of treatment(28d±7d)evaluation and record once(a total of 2 times),the study subjects before and after treatment of VAS and TCM syndrome score,and compare.Measurement data were expressed as mean±standard deviation(X±S),paired t-test was used for those who met the normal distribution,rank sum test was used for those who were not normally distributed;X~2test was used for enumeration data.Data analysis was performed using SPSS 20.0 statistical software.Results:Two patients in each group were excluded and dropped out after the end of observation.In the treatment group,1 patient had poor compliance,1 patient was lost to follow-up after oral administration of other related therapeutic drugs,and 2 patients in the control group had poor compliance and did not take oral drugs regularly as required,with a final total of 68 effective cases.In the treatment group,10 cases were cured,14 cases were markedly effective,7 cases were effective,3 cases were ineffective,and the total effective rate was 91.18%.In the control group,4 cases were cured,10 cases were markedly effective,12 cases were effective,8 cases were ineffective,and the total effective rate was 76.47%.After data analysis and comparison between the two groups,the number of cured cases in the treatment group was higher than that in the control group,the number of ineffective cases was significantly less than that in the control group,and the total effective rate was significantly higher than that in the control group.During the treatment,there were no obvious adverse reactions in the treatment group,while 2 patients in the control group showed symptoms of dry stool and poor defecation during the treatment.After being instructed to eat light diet and drink more water,the symptoms disappeared without stopping the medication and continued observation.The other 32 cases were safe and had no adverse reactions during the treatment.Conclusion:Both Juhe Wan plus or minus and Xuefuzhuyu Jiaonang can improve the clinical symptoms of male chronic pelvic floor pain syndrome with qi stagnation and blood stasis type,but Juhe Wan plus or minus can significantly reduce VAS and TCM syndrome scores,and the clinical efficacy is obviously better than Xuefuzhuyu Jiaonang,and it has better security...