| Objective: To observe the clinical efficacy difference between acupoint catgut embedding combined with oral cetirizine hydrochloride tablets and oral cetirizine hydrochloride tablets in the treatment of chronic spontaneous urticaria patients with deficiency of qi and blood,and to provide new ideas for clinical treatment.Methods: From January 2022 to December 2022,we collected 78 outpatients with chronic spontaneous urticaria of deficiency of qi and blood type who were admitted to the acupuncture and moxibustion Department,Rehabilitation Department,Dermatology Department,and Dermatology Department of Xiamen Hospital of Traditional Chinese Medicine affiliated to Fujian University of Traditional Chinese Medicine,and who met the inclusion criteria.The patients were randomly divided into observation group and control group with 39 cases in each group.The control group was treated with oral cetirizine hydrochloride tablets once a day,one tablet each time,for 8 consecutive weeks.The observation group was treated with acupoint catgut embedding therapy on the basis of the control group,once every 14 days,for 4 consecutive times,for a total of 8 weeks.Before and after treatment,the patients in the two groups filled in the Urticaria Activity Scale(UAS7),the Chronic Urticaria Quality of Life Questionnaire(CU-Q2 o L)and the Traditional Chinese Medicine Syndrome Scale,respectively,to observe the changes in the scores of the patients in the two groups before and after treatment,and evaluate the overall efficacy of the two groups.All data were statistically analyzed with SPSS23.0 software,and P<0.05 was used as the standard for statistically significant differences.Results: There were 75 patients who finally completed the study,including 38 patients in the observation group,37 patients in the control group,One exfoliative case in the observation group and two cases in the control group were excluded.1.Baseline data: There was no statistically significant difference between the two groups in terms of gender,age,course of disease and other general data scores before treatment(P>0.05),which was comparable.2.UAS7 score: There was no significant difference between the two groups in the total UAS7 score and the single UAS7 score before treatment(P>0.05).After treatment,the total score of UAS7 and the single score of UAS7 in the two groups were significantly lower than those before treatment(P<0.05);After treatment,the total score of UAS7 and the single score of UAS7 in the observation group were significantly lower than those in the control group(P<0.05).3.In terms of CU-Q2 o L score: There was no statistically significant difference in the CU-Q2 o L score between the two groups before treatment(P>0.05).The CU-Q2 o L score of patients in the two groups after treatment was significantly lower than that before treatment(P<0.05);After treatment,the CU-Q2 o L score in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).4.In terms of TCM syndrome scale score: There was no statistically significant difference between the two groups before treatment(P>0.05).After treatment,the score of TCM syndrome scale in both groups was lower than that before treatment,and the difference was statistically significant(P<0.05);The observation group was superior to the control group in improving the total score of TCM syndromes and the scores of single symptoms such as mental fatigue,white lip color,duration of wheeze and frequency of wheeze attack(P<0.05);There was no significant difference between the two groups in terms of dizziness and palpitation,insomnia,color and luster of wind,distribution of skin lesions,diameter of maximum wind,and single symptom score of tongue pulse(P>0.05).5.Overall efficacy: after the treatment,the total effective rate of the observation group was89.47%,and the total effective rate of the control group was 81.08%,which was statistically significant(P<0.05).Conclusions: Both acupoint catgut embedding combined with oral cetirizine hydrochloride tablets and oral cetirizine hydrochloride tablets alone have good effects in improving the clinical symptoms of patients with chronic spontaneous urticaria of deficiency of qi and blood,but acupoint catgut embedding combined with oral cetirizine hydrochloride tablets has more advantages in reducing the number of patients’ wind,improving the degree of itching,and alleviating the accompanying symptoms of traditional Chinese medicine,which is worthy of clinical application. |
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