| Objective:The purpose of this study is to observe the clinical efficacy of Linggui Bafa acupoint opening acupuncture combined with medicine in the treatment of peri-menopausal insomnia,and compare it with the traditional Chinese medicine group.Analyze and evaluate the difference of clinical symptoms,score scale and laboratory indexes between the two groups before and after treatment,and explore its mechanism,so as to find a more safe and efficient treatment for peri-menopausal insomnia.Methods:From December 2021 to December 2022,60 cases of perimenopausal insomnia diagnosed as heart-kidney disharmony were selected from the Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine and the gynecological clinic of Hanan Branch,and randomly divided into two groups according to the random number table method,namely,Linggui Bafa acupoint acupuncture combined with medicine group(experimental group)and simple Chinese medicine group(control group)with 30 cases in each group.In the experimental group,the eight methods of Linggui were used to open points,and then acupuncture was selected based on syndrome differentiation,combined with Huanglian Ejiao decoction.The control group was given Huanglian Ejiao decoction orally.Continuous treatment for 4 weeks.Observe the changes of each rating scale and hormone level in the two groups before,after and 4 weeks after treatment,and judge the curative effect after the treatment.Result:1.Analysis of therapeutic effect of insomnia:After treatment,the sleep disorders of the patients in the two groups were effectively improved by intra-group comparison(P<0.05).Except for daytime dysfunction,the total scores of PSQI in the test group were lower than those in the control group,and there were significant differences between the two groups(P<0.05),indicating that the effect of improving insomnia in the test group was better than that in the control group.2.Analysis of curative effect of peri-menopausal syndrome:After treatment,the PMS symptoms of the two groups were effectively improved by intra-group comparison.There was significant difference between the two groups,indicating that the treatment group was better than the control group in improving PMS symptoms.3.Analysis of Therapeutic effect of TCM Syndromes:After treatment,the two groups were compared within the group,which could effectively improve the TCM symptoms of the patients(P<0.05).There was significant difference between the two groups(P<0.05),indicating that the experimental group was better than the control group in improving TCM syndromes.4.Analysis of Therapeutic effect of Sex hormone level:After treatment,the two groups were compared within the group,both of them could reduce the FSH and increase the level of E2.There was significant difference between the two groups(P<0.05),indicating that the experimental group was superior to the control group in improving the level of sex hormones and ovarian function.5.Analysis of recurrence:After treatment,the follow-up of the two groups of effective patients showed that the recurrence rate was 7.50%in the experimental group and 16.67%in the control group,indicating that the therapeutic effect of the experimental group was better than that of the control group.Conclusion:1.Linggui Bafa acupoint acupuncture combined with Huanglian Ejiao decoction is effective in the treatment of peri-menopausal insomnia of heart-kidney disharmony type,which is effective in improving sleep disorder and TCM syndrome.2.Linggui Bafa acupoint acupuncture combined with Huanglian Ejiao decoction is effective in relieving PMS symptoms and improving ovarian function in the treatment of peri-menopausal insomnia of heart-kidney disharmony type.3.The curative effect of Linggui Bafa acupoint opening acupuncture combined with medicine in the treatment of peri-menopausal insomnia of heart-kidney disharmony type is better than that of Huanglian Ejiao decoction group,and the long-term effect is more stable. |
PDF Full Text Request