Clinical Observation Of Chaihuja Keel Oyster Soup Plus Minus Treatment Without Aura,Migraine With Insomnia(Phlegm Fever Upward Disturbance Type)

Objective: To observe the clinical effect of Chaihujia keel oyster soup in the treatment of migraine with no aura(sputum fever updisturbance type),analyze its etiology and pathogenesis,and provide theoretical basis and data support for the treatment of migraine with no aura in traditional Chinese medicine.Discover the characteristics of Chaihujia keel oyster soup and broaden its clinical application range.Methods: Sixty patients with sputum fever disturbance type migraine with sleeplessness were randomly divided into 2 groups,with 30 cases in each group.The control group was treated with flunarizine hydrochloride capsules orally.The treatment group was treated with the addition of Chaihu plus keel oyster soup plus and minus(Chaihu 12 g keel 30 g,oysters 30 g,ginseng 3g,rhubarb 6g,magnet 30 g,skullcap 9g,huanglian 9g,zhuru 9g,guizhi 12 g,poria 12 g,acacia flower,12 g tangerine peel,12 g Qingbanxia 9g,ginger 9g,jujube 6)combined with flunarizine hydrochloride capsules.The duration of treatment is 28 days.The survey recorded the number of attacks,duration,intensity,accompanying symptoms,sleep quality,and TCM syndrome points of migraine before and after treatment,and compared and analyzed the changes of Western medicine symptom points,Pittsburgh sleep quality index(PSQI)and TCM syndrome scores of the two groups.To evaluate the clinical efficacy of Chaihujia keel oyster soup in the treatment of phlegm fever updisturbance type without aura migraine with sleeplessness.SPSS19.0software was used to statistically analyze the indicators of each group and evaluate the clinical efficacy and safety of the two groups.Results: 1.Efficacy of migraine without aura: After treatment,the total effective rate of migraine without aura in the treatment group was 90.00%(27/30),the total effective rate of the control group was 83.33%(25/30),and the P<0.05 was statistically significant,and the efficacy of the treatment group was significantly better than that of the control group.2.Efficacy of sleeplessness: after treatment,the treatment group had a 96.67%(29/30)effective rate of treating sleeplessness,and the control group had a total effective rate of 50%(15/30)and a P<0.05,the difference was statistically significant,and the treatment group was significantly better than the control group.3.Efficacy of TCM symptoms: After treatment,the effective rate of TCM symptoms in the treatment group was 93.33%(28/30),and the total effective rate of the control group in the treatment of TCM symptoms was83.33%(25/30),P < 0.05,the difference was statistically significant,and the treatment group was significantly better than the control group.3.Safety evaluation: neither group of patients had obvious adverse reactions during treatment,and the safety was high.Conclusion: Chaihujia keel oyster soup plus and minus treatment of migraine without aura(sputum fever upward disturbance type)can shorten the headache attack time,reduce the intensity of headache attack,reduce the frequency of headache attack,reduce the symptoms associated with headache,improve the sleep quality of patients,reduce the symptoms of traditional Chinese medicine,and improve the total effective rate of treatment,and no obvious adverse reactions were seen.It is an effective prescription for the treatment of phlegm fever type migraine with no aura and sleeplessness,which is worthy of clinical promotion and use.